West Nile Virus Core Antibody from ROCKLAND IMMUNOCHEMICALS INC.

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Antigenic SpecificityWest Nile Virus Core
Clonepolyclonal
Host SpeciesRabbit
Reactive Speciesn/a
Isotypen/a
Formatimmunoaffinity purified
Size100 µg
Concentration1 mg/mL
ApplicationsELISA, Western Blot
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DescriptionAnti-West Nile Virus Core Antibody was affinity purified from monospecific antiserum by immunoaffinity chromatography. Cross reactivity with West Nile Virus Core from other sources has not been determined. West Nile Virus (WNV) is a member of the Flaviviridae, a plus-stranded virus family that includes St. Louis encephalitis virus, yellow fever virus, and Dengue virus. WNV was initially isolated in 1937 in the West Nile region of Uganda and has become prevalent in Africa, Asia, and Europe. It has rapidly spread across the United States with cases being observed in every continental state. Virus particles consist of a dense core made up of the core/capsid protein encapsulating the RNA genome surrounded by a membrane envelope embedded with envelope and matrix proteins which play a major role for WNV entry into target cells. The viral core protein is thought to contribute to the WNV-associated inflammation via apoptosis induced though the caspase-9 pathway as delivery of core gene delivery into the striatum of mouse brain and skeletal muscle resulted in cell death and inflammation.
ImmunogenAnti-West Nile Virus Core antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic peptide corresponding to 15 amino acids near the C-terminus of the West Nile Virus core protein.
Other NamesWest Nile Virus Core Antibody, Genome polyprotein, Core protein, NS1
Gene, Accession #WNVgp1, Gene ID: 912267, NCBI: NP_776012, UniProt: P06935
Catalog #600-401-FY3
Price$475
Order / More InfoWest Nile Virus Core Antibody from ROCKLAND IMMUNOCHEMICALS INC.
Product Specific Referencesn/a
ROCKLAND IMMUNOCHEMICALS INC.
ROCKLAND IMMUNOCHEMICALS INC.
ROCKLAND IMMUNOCHEMICALS INC.
PO Box 5199
Limerick PA 19468
P: 484-791-3823
P: 800.656.7625
F: 484.369.8654

orders@rockland.com
Technical Support: tech@rockland.com

https://www.rockland.com/

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