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Antigenic Specificity | TRIP6 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | immunoaffinity purified |
Size | 100 µg |
Concentration | 1 mg/mL |
Applications | ELISA, IF Microscopy, Western Blot |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Anti-TRIP6 Antibody was affinity purified from monospecific antiserum by immunoaffinity chromatography. Cross reactivity with TRIP6 from other sources has not been determined. TRIP6 (Thyroid receptor interacting protein 6) is a zyxin-related focal adhesion molecule involved in cell motility and antiapoptotic responses. TRIP6 is predominantly expressed in kidney, liver and lung. It has three LIM domains, a PDZ-binding motif, a Crk SH2-binding motif and/or other protein interacting domains. TRIP6 regulates NF-kB activation and interacts with RICK and TRAF2, proteins that are involved in TNF signaling. TRIP6 antagonizes Fas-induced apoptosis and promotes Fas-mediated cell migration in apoptosis-resistant glioma cells via Src-dependent phosphorylation of TRIP6 at Tyr-55. |
Immunogen | Anti-TRIP6 antibody was prepared from whole rabbit serum produced by repeated immunizations with a 15 amino acid synthetic peptide near the internal region of human TRIP6. |
Other Names | TRIP6 Antibody, OIP1, OIP-1, ZRP-1, TRIP-6, TRIP6i2, OIP1, Thyroid receptor-interacting protein 6, Opa-interacting protein 1, TR-interacting protein 6 |
Gene, Accession # | TRIP6, Gene ID: 7205, NCBI: NP_003293.2, UniProt: Q15654 |
Catalog # | 600-401-FQ2 |
Price | $475 |
Order / More Info | TRIP6 Antibody from ROCKLAND IMMUNOCHEMICALS INC. |
Product Specific References | n/a |