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Antigenic Specificity | CD4 |
Clone | 8G1B12 |
Host Species | Mouse |
Reactive Species | human, mouse, rat |
Isotype | IgG1 |
Format | Protein A purified |
Size | 100 µg |
Concentration | 1 mg/mL |
Applications | ELISA, Immunohistochemistry, IF Microscopy, Western Blot |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Anti-CD4 Monoclonal Antibody was Protein A purified. Cross reactivity with CD4 [8G1B12] from other sources has not been determined. CD4 is a member of the immunoglobulin superfamily and is implicated as associative recognition element in MHC (Major Histocompatibility Complex) class II-restricted immune response. On T-lymphocytes, it defines the helper/inducer subset. The mature 55 kd CD4 protein consists of a 372 amino acid extracellular segment composed of four tandem immunoglobulin-like VJ regions. The CD4 molecule is a major receptor for human immunodeficiency virus (HIV), binding directly to the envelope glycoprotein gp120 on HIV, with the co-receptors being CCR5 or CXCR4. It has been shown that the V-like domains are critical for binding with HIV envelope gp120. |
Immunogen | Anti-Mouse monoclonal CD4 antibody was produced by repeated immunizations in mice with a 193 amino acid recombinant protein from near the N-terminus of human CD4. |
Other Names | CD4 Antibody [8G1B12] , CD4mut |
Gene, Accession # | CD4, Gene ID: 920, NCBI: NP_000607, UniProt: P01730 |
Catalog # | 200-301-AG9 |
Price | $485 |
Order / More Info | CD4 Antibody from ROCKLAND IMMUNOCHEMICALS INC. |
Product Specific References | n/a |