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Antigenic Specificity | IL-36RN |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | immunoaffinity purified |
Size | 100 µg |
Concentration | 1 mg/mL |
Applications | ELISA, Immunohistochemistry, IF Microscopy, Western Blot |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Anti-IL-36RN antibody was affinity purified from monospecific antiserum by immunoaffinity chromatography. IL-36RN antibody is human specific. At least two isoforms of IL-36RN are known to exist. IL-36RN is a member of the interleukin 1 cytokine family whose gene and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2 (1). IL-36RN specifically inhibits the activation of NF-kappaB induced IL-36A (2). The opposing activities of these cytokines have been suggested to be involved in the regulation of skin inflammation (3). Like the IL-36 cytokines (IL-36A, IL-36B and IL-36G), IL-36RN requires post-translational processing for full agonist activity, but the cleavage mechanism is currently unknown (4). |
Immunogen | Anti-IL-36RN antibody was prepared from whole rabbit serum produced by repeated immunizations with a 19 amino acid peptide near the C-terminus of human IL-36RN. |
Other Names | IL-36RN Antibody, FIL1, FIL1D, IL1F5, IL1L1, PSORP, IL1HY1, IL1RP3, IL36RA, FIL1(DELTA), UNQ1896/PRO4342, Interleukin-36 receptor antagonist protein, FIL1 delta, IL-1RP3 |
Gene, Accession # | IL36RN, Gene ID: 26525, NCBI: NP_775262, UniProt: Q9UBH0 |
Catalog # | 600-401-BX6 |
Price | $475 |
Order / More Info | IL-36RN Antibody from ROCKLAND IMMUNOCHEMICALS INC. |
Product Specific References | n/a |