PDL2 Antibody from ROCKLAND IMMUNOCHEMICALS INC.

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Antigenic SpecificityPDL2
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse, rat
Isotypen/a
Formatimmunoaffinity purified
Size100 µg
Concentration1 mg/mL
ApplicationsELISA, Immunohistochemistry, IF Microscopy, Western Blot
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DescriptionAnti-PDL-2 Antibody was affinity purified from monospecific antiserum by immunoaffinity chromatography. Cross reactivity with PDL-2 from other sources has not been determined. Cell-mediated immune responses are initiated by T lymphocytes that are themselves stimulated by co gnate peptides bound to MHC molecules on antigen-presenting cells (APC). T-cell activation is generally self-limited as activated T cells express receptors such as PD-1 (also known as PDCD-1) that mediate inhibitory signals from the APC. PD-1 can bind two different but related ligands, PDL-1 and PDL-2, both of which are thought act as a negative regulator of T cell activation. However, it has been suggested that PDL-2 can act to stimulate an immunogenic response through and alternative receptor from PD-1. At least three isoforms of PDL-2 are known to exist; this antibody is specific to the largest isoform. PDL-2 antibody has no cross-reactivity to PDL-2.
ImmunogenAnti-PDL-2 antibody was prepared from whole rabbit serum produced by repeated immunizations with a 16 amino acid synthetic peptide from near the internal region of human PDL-2.
Other NamesPDL-2 Antibody, B7DC, Btdc, CD273, PD-L2, PDCD1L2, bA574F11.2, B7DC, Programmed cell death 1 ligand 2, Butyrophilin B7-DC, PD-1 ligand 2, PDL 2
Gene, Accession #PDCD1LG2, Gene ID: 80380, NCBI: NP_079515, UniProt: Q9BQ51
Catalog #600-401-DK8
Price$475
Order / More InfoPDL2 Antibody from ROCKLAND IMMUNOCHEMICALS INC.
Product Specific Referencesn/a
ROCKLAND IMMUNOCHEMICALS INC.
ROCKLAND IMMUNOCHEMICALS INC.
ROCKLAND IMMUNOCHEMICALS INC.
PO Box 5199
Limerick PA 19468
P: 484-791-3823
P: 800.656.7625
F: 484.369.8654

orders@rockland.com
Technical Support: tech@rockland.com

https://www.rockland.com/

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