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Antigenic Specificity | PDL2 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | immunoaffinity purified |
Size | 100 µg |
Concentration | 1 mg/mL |
Applications | ELISA, Immunohistochemistry, IF Microscopy, Western Blot |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Anti-PDL-2 Antibody was affinity purified from monospecific antiserum by immunoaffinity chromatography. Cross reactivity with PDL-2 from other sources has not been determined. Cell-mediated immune responses are initiated by T lymphocytes that are themselves stimulated by co gnate peptides bound to MHC molecules on antigen-presenting cells (APC). T-cell activation is generally self-limited as activated T cells express receptors such as PD-1 (also known as PDCD-1) that mediate inhibitory signals from the APC. PD-1 can bind two different but related ligands, PDL-1 and PDL-2, both of which are thought act as a negative regulator of T cell activation. However, it has been suggested that PDL-2 can act to stimulate an immunogenic response through and alternative receptor from PD-1. At least three isoforms of PDL-2 are known to exist; this antibody is specific to the largest isoform. PDL-2 antibody has no cross-reactivity to PDL-2. |
Immunogen | Anti-PDL-2 antibody was prepared from whole rabbit serum produced by repeated immunizations with a 16 amino acid synthetic peptide from near the internal region of human PDL-2. |
Other Names | PDL-2 Antibody, B7DC, Btdc, CD273, PD-L2, PDCD1L2, bA574F11.2, B7DC, Programmed cell death 1 ligand 2, Butyrophilin B7-DC, PD-1 ligand 2, PDL 2 |
Gene, Accession # | PDCD1LG2, Gene ID: 80380, NCBI: NP_079515, UniProt: Q9BQ51 |
Catalog # | 600-401-DK8 |
Price | $475 |
Order / More Info | PDL2 Antibody from ROCKLAND IMMUNOCHEMICALS INC. |
Product Specific References | n/a |