MYOZAP Antibody from ROCKLAND IMMUNOCHEMICALS INC.
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| Antigenic Specificity | MYOZAP |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse, rat |
| Isotype | n/a |
| Format | immunoaffinity purified |
| Size | 100 µg |
| Concentration | 1.0 mg/ml |
| Applications | ELISA, Immunohistochemistry, IF Microscopy, Western Blot |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Anti-MYOZAP Antibody was affinity purified from monospecific antiserum by immunoaffinity chromatography. Multiple isoforms of MYOZAP are known to exist. MYOZAP, also known as GRINL1A, is a 54 kDa highly conserved cardiac protein. It is strongly expressed in the heart and lung and is a novel component of intercalated disc. MYOZAP interacts with myosin phosphatase-RhoA interacting protein (MRIP) and acts as an activator of Rho-dependent SRF signaling. Knockdown study in zebrafish results in cardiomyopathy with severe dysfunction. The MYOZAP gene is part of a complex transcript unit that includes the gene for glutamate receptor, ionotropic, N-methyl D-aspartate-like 1A (GRINL1A). Transcription of this gene occurs at an upstream promoter, with two different groups of alternatively spliced variants: Gup for GRINL1A upstream transcripts and Gcom for GRINL1A combined transcripts. |
| Immunogen | Anti-MYOZAP antibody was prepared from whole rabbit serum produced by repeated immunizations with a 18 amino acid synthetic peptide near the C-terminus of human MYOZAP. |
| Other Names | MYZAP, MYOZAP Antibody, MYZAP-POLR2M, Myocardial zonula adherens protein, GRINL1A upstream protein, Gup, Myocardium-Enriched Zonula Adherens Protein, Myocardium-Enriched Zonula Occludens-1-Associated Protein, Myocardium-Enriched ZO1-Associated Protein, Myocardial Intercalated Disc Protein, GCOM1 |
| Gene, Accession # | MYZAP, Gene ID: 145781, NCBI: NP_001018110, UniProt: P0CAP1 |
| Catalog # | 600-401-CW9 |
| Price | $475 |
| Order / More Info | MYOZAP Antibody from ROCKLAND IMMUNOCHEMICALS INC. |
| Product Specific References | n/a |
ROCKLAND IMMUNOCHEMICALS INC.
ROCKLAND IMMUNOCHEMICALS INC.
PO Box 5199
Limerick PA 19468
P: 484-791-3823
P: 800.656.7625
F: 484.369.8654
orders@rockland.com
Technical Support: tech@rockland.com
https://www.rockland.com/
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