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Antigenic Specificity | ALDH3A1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | immunoaffinity purified |
Size | 100 µg |
Concentration | 1 mg/mL |
Applications | ELISA, Western Blot |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Anti-Aldh3A1 Antibody was affinity purified from monospecific antiserum by immunoaffinity chromatography. At least two isoforms of Aldh3A1 are known to exist. This antibody is predicted to have no cross-reactivity to Aldh3A2. Aldh3A1 is a member of the aldehyde dehydrogenase superfamily, a group of NAD(P)(+)-dependent enzymes that catalyze the oxidation of a wide spectrum of aliphatic and aromatic aldehydes. Aldh3A1 is highly expressed in stomach and even more strongly in cornea, representing between 5 to 50% of the water soluble protein fraction in mammalian corneas. It is thought that Aldh3A1 acts to protect the cornea from UV-induced oxidative stress by not only detoxification of reactive aldehydes by also through the direct absorption of UV energy. However, corneas from Aldh3A1-null mice are indistinguishable from those from wild-type mice; mice lacking both Aldh3A1 and Aldh1A1 showed increased cataract formation following UVB exposure, suggesting that Aldh1A1 may be able to compensate for the loss of Aldh3A1. |
Immunogen | Anti-Aldh3A1 antibody was prepared from whole rabbit serum produced by repeated immunizations with a 13 amino acid synthetic peptide near the C-terminus of the human Aldh3A1. |
Other Names | Aldh3A1 Antibody, ALDH3, ALDHIII, ALDH3, Aldehyde dehydrogenase, dimeric NADP-preferring |
Gene, Accession # | ALDH3A1, Gene ID: 218, NCBI: NP_000682, UniProt: P30838 |
Catalog # | 600-401-Y02 |
Price | $475 |
Order / More Info | ALDH3A1 Antibody from ROCKLAND IMMUNOCHEMICALS INC. |
Product Specific References | n/a |