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Antigenic Specificity | Nuclear Pore Complex |
Clone | 39C7 |
Host Species | Mouse |
Reactive Species | human, mouse, rat |
Isotype | IgG1 |
Format | Protein G purified |
Size | 100 µL |
Concentration | n/a |
Applications | IF Microscopy |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Anti-Nuclear Pore Complex antibody is directed against Nuclear Pore Complex proteins. The antibody is protein G purified from concentrated clarified cell culture supernate. This antibody is directed against yeast NPC protein. Reactivity is expected from human, mouse and rat. Nuclear Pore Complex Antibody detects Nuclear Pore Complex proteins. The nuclear pore complex (NPC) is a very large structure made up of at least 50 different proteins that span the double membrane of the nuclear envelope functioning as a gateway for macromolecular traffic between the cytoplasm and the nucleus. Discrete nuclear pore complex proteins or nucleoporins such as NUP98, NUP180 and p62 have been implicated in autoimmune disease and cancer. Patients with primary biliary cirrhosis (PBC) frequently produce autoantibodies against p62 and NUP180 while NUP98 translocations have been found in patients with acute myelogenous leukemia (AML). Anti-Nuclear Pore Complex Antibody is ideal for investigators involved in Cancer and Immunology Research. |
Immunogen | Anti-Nuclear Pore Complex Antibody (Monoclonal) was produced by repeated immunizations with yeast nuclear preparations. |
Other Names | mouse anti-Nuclear Pore Complex Antibody, NPC, NUP62, NUP, NUP133 |
Gene, Accession # | Nuclear stain of multiple gene products including Nup62, Nup133 |
Catalog # | 900-301-D98 |
Price | $475 |
Order / More Info | Nuclear Pore Complex Antibody from ROCKLAND IMMUNOCHEMICALS INC. |
Product Specific References | n/a |