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Antigenic Specificity | GRASP |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | mouse, rat |
Isotype | n/a |
Format | immunoaffinity purified |
Size | 100 µL |
Concentration | n/a |
Applications | Western Blot |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Anti-GRASP Antibody is directed against rat GRASP protein. The antibody was affinity purified from monospecific antiserum by immunoaffinity purification. Expect reactivity with the following species based on sequence homology: bovine, canine, human, rat, and mouse. Cross reactivity with GRASP from other species has not been determined. GRASP Antibody detects GRASP protein. PDZ domain-containing proteins, such as PSD-95 and GRIP are thought to play key roles in glutamate receptor plasticity. GRIP-associated proteins (GRASPs) that bind to distinct PDZ domains within GRIP also play key roles in regulation of glutamate receptor function. GRASP-1 is a neuronal rasGEF associated with GRIP and AMPA receptors in vivo. Recent work suggests that GRASP-1 may regulate neuronal ras signaling and contribute to the regulation of AMPA receptor distribution by NMDA receptor activity. Therefore, GRASP antibody is ideal for investigators involved in neuronal plasticity and remodelling and more generally in Neuroscience. |
Immunogen | Anti-GRASP Antibody was produced by repeated immunizations with synthetic peptide corresponding to amino acid residues from the C-terminal region. |
Other Names | GRIP1-associated protein 1, Glutamate receptor-interacting protein 1, GRASP1 |
Gene, Accession # | Gripap1, Gene ID: 116493, UniProt: P97879.1 |
Catalog # | 612-401-D66 |
Price | $475 |
Order / More Info | GRASP Antibody from ROCKLAND IMMUNOCHEMICALS INC. |
Product Specific References | n/a |