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Antigenic Specificity | TSC22D3 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | immunoaffinity purified |
Size | 100 µg |
Concentration | 1 mg/mL |
Applications | ELISA, Immunohistochemistry, IF Microscopy, Western Blot |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Anti-TSC22D3 Antibody was affinity purified from monospecific antiserum by immunoaffinity chromatography. Cross reactivity with TSC22D3 from other sources has not been determined. The TSC22 domain family member 3 protein (TSC22D3) is a leucine zipper protein that functions as a transcriptional regulator. The expression of TSC22D3 is stimulated by glucocorticoids and IL-10 and is thought to play a key role in the anti-inflammatory and immunosuppressive effects of these molecules. TSC22D3 can physically interact with and inhibit the activities of key inflammatory signaling mediators such NF-kB and AP-1. TSC22D3 functions as a transcriptional co-activator for various nuclear receptors and NF-kB. It has also been shown to be involved in the differentiation of mesenchymal stem cells towards osteoblasts and bone formation. |
Immunogen | Anti- TSC22D3 antibody was prepared from whole rabbit serum produced by repeated immunizations with a 16 amino acid peptide near the N-terminus of human TSC22D3. |
Other Names | TSC22D3 Antibody, DIP, GILZ, hDIP, DSIPI, TSC-22R, TSC22 domain family protein 3, DSIP-immunoreactive peptide, Protein DIP |
Gene, Accession # | TSC22D3, Gene ID: 1831, NCBI: NP_001015881.1, UniProt: Q99576 |
Catalog # | 600-401-FR2 |
Price | $475 |
Order / More Info | TSC22D3 Antibody from ROCKLAND IMMUNOCHEMICALS INC. |
Product Specific References | n/a |