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Antigenic Specificity | ANG |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | immunoaffinity purified |
Size | 100 µg |
Concentration | 1.0 mg/mL |
Applications | ELISA, IF Microscopy, Western Blot |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Anti-ANG Antibody was affinity purified from monospecific antiserum by immunoaffinity chromatography. Two alternatively spliced transcript variants have been observed. Angiogenin (ANG or ANG I) is important for the process of neovascularization and formation of new blood vessels. ANG is similar to pancreatic ribonuclease A and functions as a tRNA-specific ribonuclease that abolishes protein synthesis by specifically hydrolyzing cellular tRNAs. It interacts with endothelial cell-surface actin and may cause changes in the cell cytoskeleton. ANG is thought to be involved in the development of solid tumors and its antagonists are capable of inhibiting tumor growth. Defects in ANG are the cause of susceptibility to amyotrophic lateral sclerosis type 9 (ALS9). Angiogenin is a genetic link between ALS and PD. |
Immunogen | Anti-ANG antibody was prepared from whole rabbit serum produced by repeated immunizations with a 15 amino acid synthetic peptide near the internal region of human ANG. |
Other Names | ANG Antibody, ALS9, RAA1, HEL168, RNASE4, RNASE5, Angiogenin, Ribonuclease 5, RNase 5 |
Gene, Accession # | ANG, Gene ID: 283, NCBI: NP_001136, UniProt: P03950 |
Catalog # | 600-401-Y13 |
Price | $475 |
Order / More Info | ANG Antibody from ROCKLAND IMMUNOCHEMICALS INC. |
Product Specific References | n/a |