GluR1 phospho S831 Antibody from ROCKLAND IMMUNOCHEMICALS INC.
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| Antigenic Specificity | GluR1 phospho S831 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | mouse, rat |
| Isotype | n/a |
| Format | immunoaffinity purified |
| Size | 150 µL |
| Concentration | n/a |
| Applications | Western Blot |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Anti-GluR1 pS831 Antibody is directed against rat GluR1. The antibody was affinity purified from monospecific antiserum by immunoaffinity purification. Immunolabeling is blocked by the phosphopeptide used as antigen but not by the corresponding dephosphopeptide. Immunolabeling is completely eliminated by lambda-phosphatase treatment. Reactivity is expected from the following species based on 100% sequence homology: canine, chicken, human and mouse. GluR1 pS831 Antibody detects GluR1. The ion channels activated by glutamate are typically divided into two classes. Those that are sensitive to N-methyl-D-aspartate (NMDA) are designated NMDA receptors (NMDAR) while those activated by α-amino-3-hydroxy-5-methyl-4-isoxalone propionic acid (AMPA) are known as AMPA receptors (AMPAR). The AMPAR are comprised of four distinct glutamate receptor subunits designated (GluR1-4) and they play key roles in virtually all excitatory neurotransmission in the brain. The GluR1 subunit is widely expressed throughout the nervous system. GluR1 is potentiated by phosphorylation at Ser 831 which has been shown to be mediated by either PKC or CaM kinase II. In addition, phosphorylation of this site has been linked to synaptic plasticity as well as learning and memory. Therefore, GluR1 pS831 antibody is ideal for investigators involved in Neuroscience. |
| Immunogen | Anti-GluR1 pS831 Antibody was produced by repeated immunizations with a synthetic phospho-peptide corresponding to amino acid residues surrounding Ser 831. |
| Other Names | Glutamate receptor 1, GluR1, AMPA-selective glutamate receptor 1, GluR-A, GluR-K1, Glutamate receptor ionotropic, AMPA 1 |
| Gene, Accession # | Gria1, Gene ID: 50592, NCBI: NP_113796.1, UniProt: P19490 |
| Catalog # | 612-401-C82 |
| Price | $475 |
| Order / More Info | GluR1 phospho S831 Antibody from ROCKLAND IMMUNOCHEMICALS INC. |
| Product Specific References | n/a |
ROCKLAND IMMUNOCHEMICALS INC.
ROCKLAND IMMUNOCHEMICALS INC.
PO Box 5199
Limerick PA 19468
P: 484-791-3823
P: 800.656.7625
F: 484.369.8654
orders@rockland.com
Technical Support: tech@rockland.com
https://www.rockland.com/
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