Cyclin O Antibody from ROCKLAND IMMUNOCHEMICALS INC.
Search, find, compare suppliers for anti-Cyclin O antibody, protein, ELISA kits.
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| Antigenic Specificity | Cyclin O |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse, rat |
| Isotype | n/a |
| Format | immunoaffinity purified |
| Size | 100 µg |
| Concentration | 1 mg/mL |
| Applications | ELISA, Western Blot |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Anti-Cyclin O Antibody was affinity purified from monospecific antiserum by immunoaffinity chromatography. At least two isoforms of Cyclin O are known to exist; this antibody will recognize both isoforms. Cyclin O, also known as CCNO, has recently been identified as a Cdk1- and Cdk2-activating cyclin specific to apoptosis in lymphoid cells. Cyclin O binds to and activates Cdk2 in response to intrinsic apoptotic stimuli such as glucocorticoids or DNA-damaging agents. Suppression of Cyclin O expression by shRNA leads to the inhibition of glucocorticoid and DNA-damage-induced apoptosis due to a failure of apical caspase activation while leaving the CD95 death receptor-mediated apoptosis intact. Note: this gene, which had a previous symbol of UNG2, was erroneously identified as a uracil DNA glycosylase. A later publication identified this gene's product as a cyclin protein family member. |
| Immunogen | Anti-Cyclin O antibody was prepared from whole rabbit serum produced by repeated immunizations with a 13 amino acid synthetic peptide from near the internal region of human Cyclin O. |
| Other Names | Cyclin O Antibody, CCNU, UDG2, Cyclin-O |
| Gene, Accession # | CCNO, Gene ID: 10309, NCBI: NP_066970, UniProt: P22674 |
| Catalog # | 600-401-AR9 |
| Price | $475 |
| Order / More Info | Cyclin O Antibody from ROCKLAND IMMUNOCHEMICALS INC. |
| Product Specific References | n/a |
ROCKLAND IMMUNOCHEMICALS INC.
ROCKLAND IMMUNOCHEMICALS INC.
PO Box 5199
Limerick PA 19468
P: 484-791-3823
P: 800.656.7625
F: 484.369.8654
orders@rockland.com
Technical Support: tech@rockland.com
https://www.rockland.com/
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