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Antigenic Specificity | Kmo |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | immunoaffinity purified, no preservative |
Size | 100 µg |
Concentration | 1.02 mg/ml |
Applications | ELISA, Immunohistochemistry, IF Microscopy, Western Blot |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Anti-KMO was affinity purified from monospecific antiserum by immunoaffinity chromatography. This antibody is specific towards Kynurenine 3-monooxygenase (KMO). A BLAST analysis was used to suggest cross-reactivity with Mouse based on 100% sequence homology. Cross-reactivity with KMO from other sources has not been determined. Kynurenine 3-monooxygenase (KMO) catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). The enzyme is required for synthesis of quinolinic acid. Quinolinic acid is a neurotoxic NMDA receptor antagonist and potential endogenous inhibitor of NMDA receptor signaling in axonal targeting, synaptogenesis and apoptosis during brain development. Anti-KMO antibodies are ideal for researchers interested in Apoptosis, Neurodegeneration, and Neuroscience research. |
Immunogen | KMO affinity purified antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic peptide corresponding to an internal region surrounding 300-400aa of the mouse KMO chain. |
Other Names | rabbit anti-KMO antibody, kynurenine 3-monooxygenase, kynurenine 3-hydroxylase |
Gene, Accession # | KMO, Gene ID: 8564, NCBI: NP_003670.2, UniProt: O15229 |
Catalog # | 600-401-J25 |
Price | $475 |
Order / More Info | Kmo Antibody from ROCKLAND IMMUNOCHEMICALS INC. |
Product Specific References | n/a |