TLR5 Antibody from ROCKLAND IMMUNOCHEMICALS INC.
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| Antigenic Specificity | TLR5 |
| Clone | 85B152.5 |
| Host Species | Mouse |
| Reactive Species | human, mouse |
| Isotype | IgG2a kappa |
| Format | Protein G purified |
| Size | 100 µg |
| Concentration | 0.5 mg/mL |
| Applications | Flow Cytometry, Western Blot |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Anti-TLR5 Antibody was purified by Protein G chromatography. A BLAST analysis was used to suggest cross-reactivity with Anti-TLR5 from dog, human and mouse based on 100% homology with the immunizing sequence. Cross-reactivity with Anti-TLR5 from other sources has not been determined. Anti-TLR5 Antibody detects human TLR5. The Toll-like receptor (TLR) family in mammal comprises a family of transmembrane proteins characterized by multiple copies of leucine rich repeats in the extracellular domain and IL-1 receptor motif in the cytoplasmic domain. Like its counterparts in Drosophila, TLRs signal through adaptor molecules and could constitute an important and unrecognized component of innate immunity in humans. The TLR family is a phylogenetically conserved mediator of innate immunity that is essential for microbial recognition. TLRs characterized so far activate the MyD88/interleukin-1 receptor-associated kinase (IRAK) signaling pathway. Thirteen homologs of TLRs (TLR1-13) have been described. Toll-like receptor 5 (TLR5) expression is upregulated following exposure to bacteria or to the TLR5 agonist, flagellin. Gram-negative bacteria, stimulate monocyte/macrophage cells in a TLR5-specific, CD14-independent manner. The TLR5 receptor thus appears to be the principal means by which the innate immune system recognizes flagellated bacterial pathogens. Anti-TLR5 Antibody is ideal for investigators involved in cytokines and growth factor research. |
| Immunogen | TLR5 Antibody was produced in mice prepared by repeated immunizations with a synthetic KLH-conjugated peptide corresponding to human TLR5. |
| Other Names | TIL3, Toll-like receptor 5, Toll/interleukin-1 receptor-like protein 3 |
| Gene, Accession # | TLR5, Gene ID: 7100, NCBI: NP_003259.2, UniProt: O60602 |
| Catalog # | 200-301-I27 |
| Price | $525 |
| Order / More Info | TLR5 Antibody from ROCKLAND IMMUNOCHEMICALS INC. |
| Product Specific References | n/a |
ROCKLAND IMMUNOCHEMICALS INC.
ROCKLAND IMMUNOCHEMICALS INC.
PO Box 5199
Limerick PA 19468
P: 484-791-3823
P: 800.656.7625
F: 484.369.8654
orders@rockland.com
Technical Support: tech@rockland.com
https://www.rockland.com/
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