Histone H3 K9me1 Antibody from ROCKLAND IMMUNOCHEMICALS INC.
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| Antigenic Specificity | Histone H3 K9me1 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse, C. elegans |
| Isotype | n/a |
| Format | immunoaffinity purified |
| Size | 50 µg |
| Concentration | 0.7 mg/mL |
| Applications | Chip, Immunohistochemistry, IF Microscopy, Western Blot |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Anti-Histone H3 [Monomethyl Lys9] was affinity purified from monospecific antiserum by immunoaffinity chromatography. This antibody reacts with human Histone H3.2. A BLAST analysis was used to suggest cross-reactivity with Human, mouse, and C. elegans. Predicted to react with many species including rat, chicken, Xenopus, Drosophila, and plant based on 100% sequence homology. Cross-reactivity with Histone H3 from other sources has not been determined. Histone H3 K9 methylation is a conserved epigenetic silencer of transcription. However, for this modification to make its effect, the G9a/GLP heteromeric complex is required to methylate histone H3. Throughout development of normal tissues, DNA methylation and stable gene silencing is required to optimize cellular development. Likewise, in cancer, dysfunctions in these normal functions are required to enhance cellular proliferation. When K3K9 me1 silences the expression of RIZ1, normal apoptosis of pre-cancerous cells does not occur, and proliferation goes ahead unabated. From H3K9me1, conversion to H3K9me3 is mediated by SUVR4, at transposons and pseudogenes. Anti-Histone H3 are ideal for researchers interested in Chromatin Modifiers, Chromatin Research, Histones and Modified Histones, and Epigenetics research. |
| Immunogen | Histone H3 [Monomethyl Lys9] affinity purified antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic monomethylated peptide surrounding Lysine 9 of human Histone H3.2. |
| Other Names | rabbit anti-Histone H3 monomethyl Lys9 antibody, H3.3B, H3 histone, family 3A, H3.3AH3F3H3F3B, histone H3.3, MGC87783, MGC87782, H3K9me1 |
| Gene, Accession # | HIST2H3C, Gene ID: 126961, NCBI: NP_001005464, UniProt: Q71DI3 |
| Catalog # | 600-401-I69 |
| Price | $495 |
| Order / More Info | Histone H3 K9me1 Antibody from ROCKLAND IMMUNOCHEMICALS INC. |
| Product Specific References | n/a |
ROCKLAND IMMUNOCHEMICALS INC.
ROCKLAND IMMUNOCHEMICALS INC.
PO Box 5199
Limerick PA 19468
P: 484-791-3823
P: 800.656.7625
F: 484.369.8654
orders@rockland.com
Technical Support: tech@rockland.com
https://www.rockland.com/
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