CD8a Antibody from ROCKLAND IMMUNOCHEMICALS INC.
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| Antigenic Specificity | CD8a |
| Clone | 53-6.7 |
| Host Species | Rat |
| Reactive Species | mouse |
| Isotype | IgG2a kappa |
| Format | phycoerythrin (RPE) conjugate |
| Size | 200 µg |
| Concentration | n/a |
| Applications | Flow Cytometry, Immunohistochemistry, Immunoprecipitation |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Phycoerythrin conjugated CD8a Monoclonal Antibody was purified from tissue culture supernatant via affinity chromatography and is directed against mouse CD8a. Cross reactivity with CD8a from other sources has not been tested. Anti-CD8a is conjugated with PE under optimal conditions and the solution is free of unconjugated PE. CD8, also known as Lyt-2, Ly-2, or T8, consists of disulfide-linked α and β chains that form the α(CD8a)/β(CD8b) heterodimer and α/α homodimer. CD8a is a 34 kD protein that belongs to the immunoglobulin family. The CD8 α/β heterodimer is expressed on the surface of most thymocytes and a subset of mature TCR α/β T cells. CD8 expression on mature T cells is non-overlapping with CD4. The CD8 α/α homodimer is expressed on a subset of γ/δ TCR-bearing T cells, NK cells, intestinal intraepithelial lymphocytes, and lymphoid dendritic cells. CD8 is an antigen co-receptor on T cells that interacts with MHC class I on antigen-presenting cells or epithelial cells. CD8 promotes T cell activation through its association with the TCR complex and protein tyrosine kinase lck. |
| Immunogen | Anti-CD8a Antibody (Monoclonal) was produced by repeated immunizations with Mouse thymus or spleen . |
| Other Names | T-cell surface glycoprotein CD8 alpha chain, T-cell surface glycoprotein Lyt-2, CD8a, Cd8a, Lyt-2, Lyt2 |
| Gene, Accession # | Cd8a, Gene ID: 12525, NCBI: NP_001074579.1, UniProt: P01731 |
| Catalog # | 200-508-N77 |
| Price | $295 |
| Order / More Info | CD8a Antibody from ROCKLAND IMMUNOCHEMICALS INC. |
| Product Specific References | n/a |
ROCKLAND IMMUNOCHEMICALS INC.
ROCKLAND IMMUNOCHEMICALS INC.
PO Box 5199
Limerick PA 19468
P: 484-791-3823
P: 800.656.7625
F: 484.369.8654
orders@rockland.com
Technical Support: tech@rockland.com
https://www.rockland.com/
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