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Antigenic Specificity | Collagen Type II |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, bovine |
Isotype | n/a |
Format | fluorescein (FITC) conjugate |
Size | 50 µg |
Concentration | 1.0 mg/ml |
Applications | ELISA, Flow Cytometry, Immunohistochemistry, IF Microscopy, Immunoprecipitation, Western Blot |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This product has been prepared by immunoaffinity chromatography using immobilized antigens followed by extensive cross-adsorption against other collagens. Some class specific anti-collagens may be specific for three-dimensional epitopes which may result in diminished reactivity with denatured collagen or formalin-fixed, paraffin embedded tissues. This antibody reacts with most mammalian Type II collagens and has expected cross-reactivity with Type IV and VI and negligible cross reactivity to Type I, III and V collagens. Non-specific cross reaction of anti-collagen antibodies with other human serum proteins or non-collagen extracellular matrix proteins has not been tested. Anti-Collagen Type II Fluorescein Conjugated Antibody detects Type-II collagen which is the basis for articular cartilage and hyaline cartilage. It makes up 50% of all protein in cartilage and 85-90% of collagen of articular cartilage. Type II collagen does form fibrils which allow cartilage to entrap the proteoglycan aggregate as well as provide tensile strength to the tissue. Anti-Collagen Type II antibody is ideal for investigators involved in Immunology, Neuroscience and Signal Transduction research. |
Immunogen | Anti-Collagen Type II antibody was produced by repeated immunizations with Collagen Type II from adult human knee cartilage and bovine nasal cartilage. |
Other Names | rabbit anti-Collagen Type II antibody fluorescein conjugation, FITC conjugated rabbit anti-Collagen Type II antibody, Collagen alpha-1 (II) chain, Alpha-1 type II collagen, Cartilage collagen antibody, Chondrocalcin antibody, COL2A1 antibody |
Gene, Accession # | COL2A1, Gene ID: 1280, NCBI: NP_001835.3, UniProt: P02458 |
Catalog # | 600-402-104 |
Price | $495 |
Order / More Info | Collagen Type II Antibody from ROCKLAND IMMUNOCHEMICALS INC. |
Product Specific References | n/a |