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Antigenic Specificity | PARL |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat, chicken, primate |
Isotype | n/a |
Format | immunoaffinity purified, no preservative |
Size | 100 µg |
Concentration | 0.86 mg/ml |
Applications | ELISA, Immunohistochemistry, IF Microscopy, Western Blot |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Anti-PARL was affinity purified from monospecific antiserum by immunoaffinity chromatography. This antibody is specific towards PARL. A BLAST analysis was used to suggest cross-reactivity with Human, Mouse, Rat, Chicken, and Primate based on 100% sequence homology. Cross-reactivity with PARL (presenilin associated, rhomboid-like) from other sources has not been determined. PARL (presenilin associated, rhomboid-like) encodes a mitochondrial integral membrane protein. Following proteolytic processing of this protein, a small peptide (P-beta) is formed and translocated to the nucleus. This gene may be involved in signal transduction via regulated intramembrane proteolysis of membrane-tethered precursor proteins. Variation in this gene has been associated with increased risk for type 2 diabetes. Alternative splicing results in multiple transcript variants encoding different isoforms. Anti-PARL antibodies are ideal for researchers interested in Apoptosis, Alzheimer's Research, Neuroscience, and Mitochondrial Fusion Proteins research. |
Immunogen | PARL affinity purified antibody was prepared from whole rabbit serum produced by repeated immunization from a synthetic peptide corresponding to the C terminus region of human PARL. |
Other Names | rabbit anti-PARL antibody, p-beta, Pbeta, presenilin associated rhomboid-like protein mitochondrial, PRO2207, Mitochondrial intramembrane cleaving protease PARL, PSARL |
Gene, Accession # | PARL, Gene ID: 55486, NCBI: NP_061092.3, UniProt: Q9H300 |
Catalog # | 600-401-J27 |
Price | $475 |
Order / More Info | PARL Antibody from ROCKLAND IMMUNOCHEMICALS INC. |
Product Specific References | n/a |