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Antigenic Specificity | UHRF1BP1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | immunoaffinity purified |
Size | 100 µg |
Concentration | 1.0 mg/ml |
Applications | ELISA, Immunohistochemistry, IF Microscopy, Western Blot |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Anti-UHRF1BP1 Antibody was affinity purified from monospecific antiserum by immunoaffinity chromatography. UHRF1BP1 antibody is predicted to not cross-react with UHRF1BP1L. The Ubiquitin-like containing PHD and RING finger domains 1-binding protein 1 (UHRF1BP1), also known as ICBP90, is a transcription and cell cycle regulator. It specifically binds to the histone H3 N-terminal tail when methylated on K9 by two functional domains, a PHD finger that defines the binding specificity and an SRA (SET- and RING-associated) domain that promotes binding activity. UHRF1BP1 is required for proper heterochromatin formation in mammalian cells. Furthermore, UHRF1BP1 is thought to be a pivotal target for the ERK1/2 signaling pathway to control the proliferation of Jurkat T cells. |
Immunogen | Anti-UHRF1BP1 antibody was prepared from whole rabbit serum produced by repeated immunizations with a 17 amino acid synthetic peptide near the internal region of human UHRF1BP1. |
Other Names | UHRF1BP1 Antibody, ICBP90, C6orf107, dJ349A12.1, UHRF1-binding protein 1, ICBP90-binding protein 1 |
Gene, Accession # | UHRF1BP1, Gene ID: 54887, NCBI: NP_060224.3, UniProt: Q6BDS2 |
Catalog # | 600-401-FU1 |
Price | $475 |
Order / More Info | UHRF1BP1 Antibody from ROCKLAND IMMUNOCHEMICALS INC. |
Product Specific References | n/a |