NALP12 Antibody from ROCKLAND IMMUNOCHEMICALS INC.
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| Antigenic Specificity | NALP12 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse, rat |
| Isotype | n/a |
| Format | immunoaffinity purified |
| Size | 100 µg |
| Concentration | 1 mg/mL |
| Applications | ELISA, Immunohistochemistry, IF Microscopy, Western Blot |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Anti-NALP12 Antibody was affinity purified from monospecific antiserum by immunoaffinity chromatography. Cross reactivity with NALP12 from other sources has not been determined. NALP proteins are cytoplasmic proteins that form a subfamily within the larger CATERPILLER family and are thought to play a crucial role in cell proliferation and reproduction. Like all other NALP family members, NALP12, also known as Monarch-1, has a C-terminal leucine-rich repeat (LRR) region, an N-terminal Pyrin domain (PYD) followed by a NACHT domain, and a NACHT-associated domain. NALP12 is thought to act as an attenuating factor of inflammation by suppressing inflammatory responses such as NF-kB activation by TLR-signaling molecules MyD88, IRAK-1, TRAF6 and RIPK1 in activated monocytes. Recent evidence suggests that mutations in NALP12 result in hereditary periodic fever syndromes. |
| Immunogen | Anti-NALP12 antibody was prepared from whole rabbit serum produced by repeated immunizations with an 18 amino acid synthetic peptide near the N-terminus of human NALP12. |
| Other Names | NALP12 Antibody, RNO, PAN6, RNO2, FCAS2, NALP12, PYPAF7, CLR19.3, RNO, NACHT, LRR and PYD domains-containing protein 12, Monarch-1 |
| Gene, Accession # | NLRP12, Gene ID: 91662, NCBI: NP_653288, UniProt: P59046 |
| Catalog # | 600-401-CX8 |
| Price | $475 |
| Order / More Info | NALP12 Antibody from ROCKLAND IMMUNOCHEMICALS INC. |
| Product Specific References | n/a |
ROCKLAND IMMUNOCHEMICALS INC.
ROCKLAND IMMUNOCHEMICALS INC.
PO Box 5199
Limerick PA 19468
P: 484-791-3823
P: 800.656.7625
F: 484.369.8654
orders@rockland.com
Technical Support: tech@rockland.com
https://www.rockland.com/
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