TLR8 Antibody from ROCKLAND IMMUNOCHEMICALS INC.

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Antigenic SpecificityTLR8
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse
Isotypen/a
Formatpeptide affinity purified
Size100 µg
Concentration1.0 mg/mL
ApplicationsIF Microscopy, Western Blot
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DescriptionThis affinity-purified antibody is directed against human TLR8 protein. The product is affinity chromatography purified via peptide column. A BLAST analysis was used to suggest cross reactivity with TLR8 protein from human and mouse sources based on 100% homology with the immunizing sequence. Reactivity against homologues from other sources is not known. TLR8 (Toll Like Receptor 8). Toll-like receptors (TLRs) are signaling molecules that recognize different microbial products during infection and serve as an important link between the innate and adaptive immune responses (1-3). These proteins act through adaptor molecules such as MyD88 and TIRAP to activate various kinases and transcription factors (4,5). Like TLR7, TLR8 is localized to endosomal or lysosomal compartments (6) and stimulates the innate immune response after activation by guanosine- and uridine-rich single-stranded RNA (7). Human but not murine TLR8 confers responsiveness to the antiviral compound R-848 (8).
ImmunogenThis affinity purified antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic peptide corresponding to an internal region of human TLR8 protein.
Other NamesCD 288 antibody, CD288 antibody, CD288 antigen antibody, MGC119599 antibody, MGC119600 antibody, TLR 8 antibody, Toll Like Receptor 8 antibody
Gene, Accession #TLR8, Gene ID: 51311, NCBI: 74054102, UniProt: Q9NR97
Catalog #600-401-958
Price$475
Order / More InfoTLR8 Antibody from ROCKLAND IMMUNOCHEMICALS INC.
Product Specific Referencesn/a
ROCKLAND IMMUNOCHEMICALS INC.
ROCKLAND IMMUNOCHEMICALS INC.
ROCKLAND IMMUNOCHEMICALS INC.
PO Box 5199
Limerick PA 19468
P: 484-791-3823
P: 800.656.7625
F: 484.369.8654

orders@rockland.com
Technical Support: tech@rockland.com

https://www.rockland.com/

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