Edit |   |
---|---|
Antigenic Specificity | hLeo1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | serum |
Size | 100 µL |
Concentration | Neat |
Applications | Western Blot |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Anti-hLeo1 Antibody is monospecific antiserum processed by delipidation and defibrination followed by sterile filtration. This product reacts with human hLeo1. Cross reactivity with hLeo1 from other sources is not known. PAF is a five-subunit protein complex composed of Paf1, Cdc73, Leo1, Rtf1 and Ctr9, which was first purified from yeast. The yeast PAF (yPAF) complex interacts with RNA polymerase II and coordinates the setting of histone marks associated with active transcription. The human PAF (hPAF) complex shares four subunits with yPAF (hCtr9, hPaf1, hLeo1 and Cdc73), but contains an additional higher eukaryotic-specific subunit, hSki8. In addition to coordinating events during transcription (initiation, promoter clearance and elongation); PAF also coordinates events in RNA quality control. Anti-hLeo1 Antibody is ideal for research in Gene Expression, Transcription and Epigenetics. |
Immunogen | Anti-hLeo1 Antibody was produced in rabbits by repeated immunizations with a full length recombinant protein of human Leo1 (component of the human PAF1/RNA polymerase ll complex). |
Other Names | RNA polymerase-associated protein LEO1, Replicative senescence down-regulated leo1-like protein, RDL |
Gene, Accession # | LEO1, Gene ID: 123169, NCBI: NP_001273359.1, UniProt: Q8WVC0 |
Catalog # | 100-401-V37 |
Price | $445 |
Order / More Info | hLeo1 Antibody from ROCKLAND IMMUNOCHEMICALS INC. |
Product Specific References | n/a |