MD-2 Antibody from ROCKLAND IMMUNOCHEMICALS INC.
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| Antigenic Specificity | MD-2 |
| Clone | 9F1B1 |
| Host Species | Mouse |
| Reactive Species | human, mouse |
| Isotype | IgG1 |
| Format | immunoaffinity purified |
| Size | 100 µg |
| Concentration | 1.0 mg/ml |
| Applications | ELISA, Immunohistochemistry, IF Microscopy, Western Blot |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Anti-MD-2 Monoclonal Antibody was immunoaffinity chromatography purified IgG. Cross reactivity with MD-2 [9F1B1] from other sources has not been determined. MD-2 is a member of the Toll/interleukin-1 receptor (TIR) family, a group of proteins that include the Toll-like receptors (TLRs). TLRs are signaling molecules that recognize different pathogen-associated molecular patterns (PAMPs) and serve as an important link between the innate and adaptive immune responses. TLR4, the major signaling receptor for lipopolysaccharide (LPS), requires the binding of MD-2 to its extracellular region for maximal response to LPS. The specificity of this response is determined by the species of MD-2; e.g., human MD-2 transfected into mouse cells can cause mouse TLR4 to react to LPS analogs that are normally antagonistic to human but not mouse TLR4. |
| Immunogen | Anti-MD-2 antibody was produced in mice by repeated immunizations with a recombinant protein corresponding to amino acids 2 to 160 of human MD-2 |
| Other Names | MD-2 Antibody [9F1B1] , MD2, MD-2, ly-96, ESOP-1 |
| Gene, Accession # | LY96, Gene ID: 23643, NCBI: NP_056179, UniProt: Q9Y6Y9 |
| Catalog # | 200-301-CS5 |
| Price | $485 |
| Order / More Info | MD-2 Antibody from ROCKLAND IMMUNOCHEMICALS INC. |
| Product Specific References | n/a |
ROCKLAND IMMUNOCHEMICALS INC.
ROCKLAND IMMUNOCHEMICALS INC.
PO Box 5199
Limerick PA 19468
P: 484-791-3823
P: 800.656.7625
F: 484.369.8654
orders@rockland.com
Technical Support: tech@rockland.com
https://www.rockland.com/
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