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Antigenic Specificity | TLR11 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | mouse |
Isotype | n/a |
Format | ion exchange purified |
Size | 100 µg |
Concentration | 1 mg/mL |
Applications | ELISA, IF Microscopy, Western Blot |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Anti-TLR11 Antibody is purified by ion exchange chromatography. Cross reactivity with TLR11 from other sources has not been determined. Toll-like receptors (TLRs) are signaling molecules that recognize different microbial products during infection and serve as an important link between the innate and adaptive immune responses. These proteins act through adaptor molecules such as MyD88 and TIRAP to activate various kinases and transcription factors. TLR11 is one of three mouse TLRs that lack a human ortholog. It is activated specifically by uropathogenic bacteria, and mice lacking TLR11 showed a much greater susceptibility to uropathogenic infections, indicating a potentially important role for TLR11 in preventing infections in the urogenital system. |
Immunogen | Anti-TLR11 antibody was prepared from whole rabbit serum produced by repeated immunizations with a peptide corresponding to 16 amino acids between the internal region and C-terminus of mouse TLR11. |
Other Names | TLR11 Antibody, Gm287, Gm287, Toll-like receptor 11 |
Gene, Accession # | Tlr11, Gene ID: 239081, NCBI: NP_991388.2, UniProt: Q6R5P0 |
Catalog # | 200-401-FF8 |
Price | $475 |
Order / More Info | TLR11 Antibody from ROCKLAND IMMUNOCHEMICALS INC. |
Product Specific References | n/a |