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Antigenic Specificity | Syntaxin |
Clone | SP8 |
Host Species | Mouse |
Reactive Species | human, rat, hamster, porcine |
Isotype | IgG1 |
Format | Protein G purified |
Size | 100 µL |
Concentration | n/a |
Applications | Immunohistochemistry, Western Blot |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Anti-Syntaxin Monoclonal Antibody is directed against Syntaxin. Syntaxin antibody was purified by Protein G chromatography from cell culture supernatant. Reactivity is expected from rat, pig and hamster. Cross reactivity with syntaxin from other species has not been determined. Syntaxin antibody detects Syntaxin-1A protein which is part of a family of proteins involved in the docking of synaptic vesicles with the plasma membrane. Syntaxin, along with synaptobrevin and SNAP-25, forms the SNARE complex which mediates synaptic vesicle fusion and exocytosis. Binding of Munc18-1 to the N-terminus of syntaxin 1 has been demonstrated to be essential for exocytic membrane fusion. Decreased levels of phosphorylated syntaxin 1 in the prefrontal cortex have recently been correlated with schizophrenia. Anti-Syntaxin Antibody is ideal for investigators involved in Cell Signaling, Neuroscience, Signal Transduction research. |
Immunogen | Anti-Syntaxin Monoclonal Antibody was produced in mouse by repeated immunizations with Synaptic immunoprecipitate (crude) from human brain. |
Other Names | Neuron-specific antigen HPC-1, Syntaxin-1A |
Gene, Accession # | STX1A, Gene ID: 6804, NCBI: AAA20940.1, UniProt: Q16623 |
Catalog # | 200-301-E40 |
Price | $485 |
Order / More Info | Syntaxin Antibody from ROCKLAND IMMUNOCHEMICALS INC. |
Product Specific References | n/a |