CD20 Antibody from ROCKLAND IMMUNOCHEMICALS INC.

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Antigenic SpecificityCD20
Clone2H7
Host SpeciesMouse
Reactive Specieshuman
IsotypeIgG2b kappa
Formatallophycocyanin (APC) conjugate
Size500 µL
Concentrationn/a
ApplicationsFlow Cytometry, Immunohistochemistry, Immunoprecipitation
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DescriptionAllophycocyanin conjugated CD20 Monoclonal Antibody was purified from tissue culture supernatant via affinity chromatography and is directed against human CD20. Reactivity is observed against human CD20 Chimpanzee, Baboon, Cynomolgus, Rhesus, Pigtailed Macaque, Capuchin Monkey, and Squirrel Monkey. Cross reactivity with CD20 from other sources has not been tested. Anti-CD20 is conjugated with APC under optimal conditions and the solution is free of unconjugated APC. CD20 is a 33-37 kD, four transmembrane spanning protein, also known as B1 and Bp35. CD20 is expressed on pre-B-cells, resting and activated B cells (not plasma cells), some follicular dendritic cells, and at low levels on a T cell subset. CD20 is heavily phosphorylated on activated B cells and malignant B cells. Homo-oligomeric complexes of CD20 are thought to form Ca2+ conductive ion channels in the plasma membrane of B cells. The CD20 molecule is involved in B-cell activation and is associated with various Src family kinases (Lyn, Lck, Fyn). It exists in a complex with MHC class I and II, CD53, CD81, and CD82.
ImmunogenAnti-CD20 Antibody (Monoclonal) was produced by repeated immunizations with CD20 antigen.
Other NamesB-lymphocyte antigen CD20, B-lymphocyte surface antigen B1, Bp35, Leukocyte surface antigen Leu-16, Membrane-spanning 4-domains subfamily A member 1, CD20
Gene, Accession #MS4A1, Gene ID: 931, NCBI: NP_068769.2, UniProt: P11836
Catalog #200-326-N64
Price$315
Order / More InfoCD20 Antibody from ROCKLAND IMMUNOCHEMICALS INC.
Product Specific Referencesn/a
ROCKLAND IMMUNOCHEMICALS INC.
ROCKLAND IMMUNOCHEMICALS INC.
ROCKLAND IMMUNOCHEMICALS INC.
PO Box 5199
Limerick PA 19468
P: 484-791-3823
P: 800.656.7625
F: 484.369.8654

orders@rockland.com
Technical Support: tech@rockland.com

https://www.rockland.com/

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