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Antigenic Specificity | BAFF Receptor |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | immunoaffinity purified |
Size | 100 µg |
Concentration | 1 mg/mL |
Applications | ELISA, Immunohistochemistry, IF Microscopy, Western Blot |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Anti-BAFF Receptor Antibody was affinity purified from monospecific antiserum by immunoaffinity chromatography. Cross reactivity with BAFF Receptor from other sources has not been determined. Members in the TNF superfamily regulate immune responses and induce apoptosis. A novel member in the TNF family was recently identified by several groups and designated BAFF, BLyS, TALL-1, THANK, and zTNF4. BAFF/BLyS was characterized as a B cell activator since it induced B cell proliferation and immunoglobulin secretion. Two receptors, TACI and BCMA, for BAFF were originally identified. A third receptor was identified recently and designated BAFF-R and BR3 for BLyS receptor 3. Unlike BCMA and TACI, which bind to BAFF and April, BAFF-R/BR3 is specific for BAFF and plays a predominant role in BAFF induced B cell development and survival. BAFF and its receptors are involved in B cell associated autoimmune diseases, and activate NF-kB and c-jun N-terminal kinase. |
Immunogen | Anti-BAFF Receptor antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic peptide corresponding to amino acids near the C-terminus of human BAFF Receptor The peptide sequence is identical between human and mouse origin. |
Other Names | BAFF Receptor Antibody, BAFFR, CD268, CVID4, BAFF-R, BROMIX, prolixin, BAFFR, BR3, Tumor necrosis factor receptor superfamily member 13C, B-cell-activating factor receptor |
Gene, Accession # | TNFRSF13C, Gene ID: 115650, NCBI: AAK91826, UniProt: Q96RJ3 |
Catalog # | 600-401-Z20 |
Price | $475 |
Order / More Info | BAFF Receptor Antibody from ROCKLAND IMMUNOCHEMICALS INC. |
Product Specific References | n/a |