JARID1C Antibody from ROCKLAND IMMUNOCHEMICALS INC.

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Antigenic SpecificityJARID1C
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse
Isotypen/a
Formatserum
Size100 µL
Concentrationneat
ApplicationsELISA, Western Blot
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DescriptionAnti-Jarid1c Antibody is monospecific antiserum processed by delipidation and defibrination followed by sterile filtration. Cross reactivity with Jarid1c from other species not tested. Jarid1c is a histone demethylase which specifically demethylates lysine 4 of histone H3, thereby playing a internal role in the regulation of transcription and chromatin remodeling. Jarid1c demethylates the trimethylated and dimethylated lysine 4, but not the monomethylated form. Further, Jarid1c participates in transcriptional repression of neuronal genes by recruiting histone deacetylases and REST at neuron-restrictive silencer elements. Mutations in the Jarid1c gene have been associated with X-linked mental retardation. Anti-Jarid1c Antibody is ideal for research in Epigenetics, Gene Expression and Neuroscience.
ImmunogenAnti-JARID1C Antibody was produced in rabbits by repeated immunizations with three different synthetic peptides containing sequences from the inner part of the mouse Jarid1c protein.
Other NamesLysine-specific demethylase 5C, Histone demethylase JARID1C, Jumonji/ARID domain-containing protein 1C, Protein SmcX, Protein Xe169, DXS1272E, JARID1C, SMCX, XE169
Gene, Accession #KDM5C, Gene ID: 8242, NCBI: NP_001140174.1, UniProt: P41229
Catalog #100-401-W42
Price$445
Order / More InfoJARID1C Antibody from ROCKLAND IMMUNOCHEMICALS INC.
Product Specific Referencesn/a
ROCKLAND IMMUNOCHEMICALS INC.
ROCKLAND IMMUNOCHEMICALS INC.
ROCKLAND IMMUNOCHEMICALS INC.
PO Box 5199
Limerick PA 19468
P: 484-791-3823
P: 800.656.7625
F: 484.369.8654

orders@rockland.com
Technical Support: tech@rockland.com

https://www.rockland.com/

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