NMDA R2A Antibody from ROCKLAND IMMUNOCHEMICALS INC.

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Antigenic SpecificityNMDA R2A
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse, rat
Isotypen/a
Formatserum
Size50 µL
ConcentrationTitrated value sufficient to run approximately 10 mini blots.
ApplicationsWestern Blot
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DescriptionAnti-NMDA R2A antibody is directed against NMDA R2A protein. The antibody was prepared from monospecific neat serum. Anti-NMDA R2A antibodies exhibit no reactivity towards the NR2B and NR2C subunits. Immunolabeling is blocked by pre-adsorption of the antibody with the fusion protein used to generate the antibody. Reactivity is reported to occur with rat, mouse and human. NMDA R2A Antibody detects NMDA R2A protein. The NMDA receptor (NMDAR) plays an essential role in memory, neuronal development and it has also been implicated in several disorders of the central nervous system including Alzheimer's, epilepsy and ischemic neuronal cell death. The NMDA receptor is also one of the principal molecular targets for alcohol in the CNS. The NMDAR is also potentiated by protein phosphorylation. The rat NMDAR1 (NR1) was the first subunit of the NMDAR to be cloned. The NR1 protein can form NMDA activated channels when expressed in Xenopus oocytes but the currents in such channels are much smaller than those seen in situ. Channels with more physiological characteristics are produced when the NR1 subunit is combined with one or more of the NMDAR2 (NR2 A-D) subunits. Anti-NMDA R2A Antibody is ideal for investigators involved in Neuroscience, Cell Signaling, and Signal Transduction research.
ImmunogenAnti-NMDA R2A Antibody was produced by repeated immunizations with fusion protein from the C-terminal region of the NR2A subunit
Other NamesGlutamate [NMDA] receptor subunit epsilon-1, N-methyl D-aspartate receptor subtype 2A, NMDAR2A, NR2A, Grin2a
Gene, Accession #Grin2a, Gene ID: 24409, UniProt: Q00959
Catalog #100-401-C86
Price$475
Order / More InfoNMDA R2A Antibody from ROCKLAND IMMUNOCHEMICALS INC.
Product Specific Referencesn/a
ROCKLAND IMMUNOCHEMICALS INC.
ROCKLAND IMMUNOCHEMICALS INC.
ROCKLAND IMMUNOCHEMICALS INC.
PO Box 5199
Limerick PA 19468
P: 484-791-3823
P: 800.656.7625
F: 484.369.8654

orders@rockland.com
Technical Support: tech@rockland.com

https://www.rockland.com/

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