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Antigenic Specificity | TAO2 phospho S181 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | immunoaffinity purified |
Size | 100 µL |
Concentration | n/a |
Applications | Western Blot |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Anti-TAO2 pS181 Antibody is directed against human TAO2 protein phosphorylated at Ser181. TAO2 pS181 antibodies are prepared from monospecific antiserum by immunoaffinity chromatography using phospho peptide coupled to agarose beads followed by solid phase adsorption(s) against non-phospho peptide and non-specific peptide to remove any unwanted reactivities. Assay by immunoelectrophoresis resulted in a single precipitin arc against anti-Rabbit Serum. Immunolabeling is completely eliminated by treatment with lambda-phosphatase. Reactivity is expected from the following species based on 100% sequence homology: zebra fish, xenopus, finch and canine. TAO2pS181 Antibody detects TAO2. In vitro, TAO (thousand and one amino acid) protein kinase 2 (TAO2) activates MAP/ERK kinases (MEKs) 3, 4, and 6 toward their substrates p38 MAP kinase JNK/SAPK. This and more recent work has led to the proposal that the TAO protein kinases play an essential role in signaling from physiological agonists to the stress-responsive p38 MAPKs. Autophosphorylation of TAO2 may play a role in the mechanism of TAO2 activation. The MEK binding domain of TA2O is autophosphorylated on both serine and threonine residues and Ser181 is located within this domain. Anti-TAO2 pS181 Antibody is ideal for investigators involved in Cell Signaling, Neuroscience, Signal Transduction research. |
Immunogen | Anti-TAO2 pS181 Antibody was produced in rabbit by repeated immunizations with synthetic phospho-peptide corresponding to amino acid residues surrounding Ser181 of TAO2 protein. |
Other Names | Serine/threonine-protein kinase TAO2, Kinase from chicken homolog C, hKFC-C, Prostate-derived sterile 20-like kinase 1, PSK-1, Thousand and one amino acid protein kinase 2 |
Gene, Accession # | TAOK2, Gene ID: 9344, UniProt: Q9UL54 |
Catalog # | 600-401-E41 |
Price | $475 |
Order / More Info | TAO2 phospho S181 Antibody from ROCKLAND IMMUNOCHEMICALS INC. |
Product Specific References | n/a |