GABA(B) Receptor 2 phospho S783 Antibody from ROCKLAND IMMUNOCHEMICALS INC.
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| Antigenic Specificity | GABA(B) Receptor 2 phospho S783 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | mouse, rat |
| Isotype | n/a |
| Format | immunoaffinity purified |
| Size | 100 µL |
| Concentration | n/a |
| Applications | IF Microscopy, Western Blot |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Anti-GABA(B) Receptor 2 pS783 Antibody is directed against rat phosphorylated GABA(B) Receptor 2. The antibody was affinity purified from monospecific antiserum by immunoaffinity purification. Immunolabeling of the GABAB R2 band is completely blocked by lambda-phosphatase treatment. Reactivity is expected from the following species based on 100% sequence homology: bovine, canine, chicken, human, mouse, Xenopus and non-human primates. Anti-GABA(B) Receptor 2 pS783 Antibody detects phosphorylated GABA(B) Receptor 2. Gamma-aminobutyric acid (GABA) is the primary inhibitory neurotransmitter in the central nervous system. There are two major classes of GABA receptors: the GABAA and the GABAB subtype of receptors. GABAB receptors are heterodimeric G protein-coupled receptors that mediate slow synaptic inhibition in the central nervous system. It has recently been demonstrated that AMPK binds directly to GABAB receptors and phosphorylates S783 in the cytoplasmic tail of the R2 subunit and that S783 plays a critical role in enhancing neuronal survival after ischemia as phosphorylation of S783 is evident in many brain regions and is increased dramatically after ischemic injury to the brain. GABA(B) Receptor 2 pS783 antibody is ideal for investigators involved in Neuroscience. |
| Immunogen | Anti-GABA(B) Receptor 2 pS783 Antibody was produced by repeated immunizations with synthetic phospho-peptide corresponding to amino acid residues surrounding Ser 783 of rat GABAB R2. |
| Other Names | Gamma-aminobutyric acid type B receptor subunit 2, GABA-B-R2, GABA-BR2, GABABR2, Gb2, G-protein coupled receptor 51 |
| Gene, Accession # | Gabbr2, Gene ID: 83633, NCBI: 8393403, UniProt: O88871 |
| Catalog # | 612-401-D53 |
| Price | $475 |
| Order / More Info | GABA(B) Receptor 2 phospho S783 Antibody from ROCKLAND IMMUNOCHEMICALS INC. |
| Product Specific References | PubMed: 32398643 |
ROCKLAND IMMUNOCHEMICALS INC.
ROCKLAND IMMUNOCHEMICALS INC.
PO Box 5199
Limerick PA 19468
P: 484-791-3823
P: 800.656.7625
F: 484.369.8654
orders@rockland.com
Technical Support: tech@rockland.com
https://www.rockland.com/
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