DOK1 Antibody from ROCKLAND IMMUNOCHEMICALS INC.

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Antigenic SpecificityDOK1
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman
Isotypen/a
Formatimmunoaffinity purified
Size100 µg
Concentration1 mg/mL
ApplicationsELISA, IF Microscopy, Western Blot
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DescriptionAnti-DOK1 Antibody was affinity purified from monospecific antiserum by immunoaffinity chromatography. Cross reactivity with DOK1 from other sources has not been determined. Signals from most growth factors and cytokines are transduced by receptor tyrosine kinases or non-receptor tyrosine kinases. Activated tyrosine kinases phosphorylate their substrates, which mediate the cellular response to extracellular stimuli. A long-sought major substrate termed p62dok (downstream of tyrosine kinase) for many tyrosine kinases including c-kit, v-abl, v-Fps, v-Src, v-Fms, and activated EGF, PDGF, IGF, VEGF and insulin receptors was identified recently from human and mouse by several laboratories. Upon phosphorylation, p62dok forms a complex with the ras GTPase-activating protein (RasGAP). p62dok represents a new family with very recently identified p56dok.
ImmunogenAnti-DOK1 antibody was prepared from whole rabbit serum produced by repeated immunizations with a peptide corresponding to amino acids near the C-terminus of human DOK1.
Other NamesDOK1 Antibody, TP1, TLP1, p240, TROVE1, VAULT2, Docking protein 1, Downstream of tyrosine kinase 1
Gene, Accession #DOK1, Gene ID: 7011, NCBI: AAC51127, UniProt: Q99704
Catalog #600-401-AW9
Price$475
Order / More InfoDOK1 Antibody from ROCKLAND IMMUNOCHEMICALS INC.
Product Specific Referencesn/a
ROCKLAND IMMUNOCHEMICALS INC.
ROCKLAND IMMUNOCHEMICALS INC.
ROCKLAND IMMUNOCHEMICALS INC.
PO Box 5199
Limerick PA 19468
P: 484-791-3823
P: 800.656.7625
F: 484.369.8654

orders@rockland.com
Technical Support: tech@rockland.com

https://www.rockland.com/

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