DDX60 Antibody from ROCKLAND IMMUNOCHEMICALS INC.
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| Antigenic Specificity | DDX60 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse, rat |
| Isotype | n/a |
| Format | immunoaffinity purified |
| Size | 100 µg |
| Concentration | 1mg/ml |
| Applications | ELISA, IF Microscopy, Western Blot |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Anti-DDX60 Antibody was affinity purified from monospecific antiserum by immunoaffinity chromatography. At least three isoforms of DDX60 are known to exist; this antibody will detect all three isoforms. DDX60 is a DEXD/H Box RNA helicase and the human homolog of the S. cerevisiae Ski2, a cofactor of RNA exosome. Expression of DDX60 increases after viral infection and binds to endogenous RIG-I, a cytoplasmic viral RNA sensor, as well as other RIG-I-like receptors such as MDA5 and LGP2. These proteins activate TBK1 and IKK-e, signaling IRF3 and NF-kB-responsive genes in the innate immune response pathway. DDX60 is required for the RIG-I- or MDA5-dependent response to viral infection, but is dispensable for TLR3-mediated signaling. |
| Immunogen | Anti-DDX60 antibody was prepared from whole rabbit serum produced by repeated immunizations with a 17 amino acid synthetic peptide near the internal region of human DDX60. |
| Other Names | DDX60 Antibody, Probable ATP-dependent RNA helicase DDX60, DEAD box protein 60 |
| Gene, Accession # | DDX60, Gene ID: 55601, NCBI: NP_060101, UniProt: Q8IY21 |
| Catalog # | 600-401-AU6 |
| Price | $475 |
| Order / More Info | DDX60 Antibody from ROCKLAND IMMUNOCHEMICALS INC. |
| Product Specific References | n/a |
ROCKLAND IMMUNOCHEMICALS INC.
ROCKLAND IMMUNOCHEMICALS INC.
PO Box 5199
Limerick PA 19468
P: 484-791-3823
P: 800.656.7625
F: 484.369.8654
orders@rockland.com
Technical Support: tech@rockland.com
https://www.rockland.com/
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