Connexin 43 Antibody from ROCKLAND IMMUNOCHEMICALS INC.

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Antigenic SpecificityConnexin 43
Clonepolyclonal
Host SpeciesRabbit
Reactive Speciesrat
Isotypen/a
Formatimmunoaffinity purified
Size100 µL
Concentrationn/a
ApplicationsELISA, Western Blot
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DescriptionAnti-Connexin 43 antibody is directed against rat Connexin 43. Anti-Connexin 43 antibody was affinity purified from monospecific antiserum by immunoaffinity purification. Anti-Connexin 43 antibody recognizes Connexin 43 from rat sources. Cross reactivity with Connexin 43 from other species has not been determined. However, reactivity is also expected from the following species based on 100% sequence homology: chicken, canine, finch, human, mouse non-human primate, sheep, Xenopus, zebra fish. Connexin 43 Antibody detects connexin which is thought to play a key role in development and may also be involved in epilepsy. Connexin 43 antibody recognizes Connexin 43 which forms gap-junctional channels and regulates the permeability of these gap junctions to small organic molecules. Permeability of connexin43 is known to be regulated by phosphorylation at er368 by protein kinase C. Phosphorylation of Ser368 by PKC induces a conformational change of connexin43 that results in a decrease in gap junction permeability. Anti-Connexin 43 Antibody is ideal for investigators involved in Neuroscience and Cell Signaling.
ImmunogenAnti-Connexin 43 Antibody was produced in rabbit by repeated immunizations with synthetic peptide corresponding to amino acid residues from the C-terminal region conjugated to KLH.
Other NamesGap junction alpha-1 protein, Gap junction 43 kDa heart protein, CX43, Connexin-43
Gene, Accession #Gja1, Gene ID: 24392, NCBI: AAA41000.1, UniProt: P08050
Catalog #612-401-D22
Price$475
Order / More InfoConnexin 43 Antibody from ROCKLAND IMMUNOCHEMICALS INC.
Product Specific Referencesn/a
ROCKLAND IMMUNOCHEMICALS INC.
ROCKLAND IMMUNOCHEMICALS INC.
ROCKLAND IMMUNOCHEMICALS INC.
PO Box 5199
Limerick PA 19468
P: 484-791-3823
P: 800.656.7625
F: 484.369.8654

orders@rockland.com
Technical Support: tech@rockland.com

https://www.rockland.com/

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