Edit |   |
---|---|
Antigenic Specificity | NIPSNAP |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | immunoaffinity purified |
Size | 100 µg |
Concentration | 1 mg/mL |
Applications | ELISA, Immunohistochemistry, IF Microscopy, Western Blot |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Anti-NIPSNAP Antibody was affinity purified from monospecific antiserum by immunoaffinity chromatography. Cross reactivity with NIPSNAP from other sources has not been determined. NIPSNAP is a member of an evolutionarily well conserved gene family and has a strong sequence similarity to the central portion of a protein encoded by C. elegans chromosome III between a 4-nitrophenylphosphatase (NIP) domain and non-neuronal SNAP25-like protein. Recent studies have indicated that NIPSNAP is involved in the regulation of the Ca2+-selective transient receptor potential vanilloid channel 6 (TRPV6). NIPSNAP1 associates with TRPV6 at the plasma membrane and inhibits TRPV6 currents. Other studies show that NIPSNAP's expression is reduced in the phenylketonuria (PKU) mouse brain, suggesting that NIPSNAP may play a role in memory. |
Immunogen | Anti-NIPSNAP antibody was prepared from whole rabbit serum produced by repeated immunizations with a 18 amino acid synthetic peptide from near the C-terminus of human NIPSNAP. |
Other Names | NIPSNAP Antibody, Protein NipSnap homolog 1, NipSnap1 |
Gene, Accession # | NIPSNAP1, Gene ID: 8508, NCBI: NP_003625, UniProt: Q9BPW8 |
Catalog # | 600-401-DB5 |
Price | $475 |
Order / More Info | NIPSNAP Antibody from ROCKLAND IMMUNOCHEMICALS INC. |
Product Specific References | n/a |