JMJD1B Antibody from ROCKLAND IMMUNOCHEMICALS INC.
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| Antigenic Specificity | JMJD1B |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse, rat |
| Isotype | n/a |
| Format | immunoaffinity purified |
| Size | 100 µg |
| Concentration | 1 mg/mL |
| Applications | ELISA, Immunohistochemistry, IF Microscopy, Western Blot |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Anti-JMJD1B Antibody was affinity purified from monospecific antiserum by immunoaffinity chromatography. This antibody will not cross-react with JMJD1A or JMJD1C. The jumonji domain containing 1B protein (JMJD1B) was originally discovered as a candidate for the myeloid leukemia tumor suppressor gene. Besides CD34+ cells and acute myeloid leukemia (AML) cell lines, JMJD1B mRNA is highly expressed in liver, heart, kidney, skeletal muscle, and placenta tissues. The JMJD1B gene is localized to a region of chromosome 5q31, which is frequently deleted in myeloid leukemias and myelodysplasias and expression of JMJD1B in a del(5q) cell line results in suppression of clonogenic growth suggesting that JMJD1B may function as a tumor suppressor. In contrast, JMJD1B gene copy number and mRNA expression level was increased in several non-small cell lung cancers indicating that the role of JMJD1B in cancer formation and progression is more complex than originally postulated. At least three isoforms of JMJD1B are known to exist. |
| Immunogen | Anti-JMJD1B antibody was prepared from whole rabbit serum produced by repeated immunizations with a 20 amino acid synthetic peptide from near the internal region of human JMJD1B. |
| Other Names | JMJD1B Antibody, 5qNCA, NET22, C5orf7, JMJD1B, JHDM2B, KIAA1082, Lysine-specific demethylase 3B, JmjC domain-containing histone demethylation protein 2B |
| Gene, Accession # | KDM3B, Gene ID: 51780, NCBI: EAW62141, UniProt: Q7LBC6 |
| Catalog # | 600-401-CB4 |
| Price | $475 |
| Order / More Info | JMJD1B Antibody from ROCKLAND IMMUNOCHEMICALS INC. |
| Product Specific References | n/a |
ROCKLAND IMMUNOCHEMICALS INC.
ROCKLAND IMMUNOCHEMICALS INC.
PO Box 5199
Limerick PA 19468
P: 484-791-3823
P: 800.656.7625
F: 484.369.8654
orders@rockland.com
Technical Support: tech@rockland.com
https://www.rockland.com/
Profile of ROCKLAND IMMUNOCHEMICALS INC.