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Antigenic Specificity | IL-17RE |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | immunoaffinity purified |
Size | 100 µg |
Concentration | 1 mg/mL |
Applications | ELISA, Western Blot |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Anti-IL-17RE Antibody was affinity purified from monospecific antiserum by immunoaffinity chromatography. Cross reactivity with IL-17RE from other sources has not been determined. The interleukin 17 receptor E (IL-17RE) shares limited similarity to the receptor of IL-17A, a ubiquitous type I membrane glycoprotein that with IL-17A plays a pathogenic role in many inflammatory and autoimmune diseases such as rheumatoid arthritis. IL-17RE is the functional receptor of IL-17C and has been suggested to mediate mucosal immunity to infection with intestinal pathogens. IL-17C is produced by epithelia in response to bacterial challenge and binds to a receptor complex formed by IL-17RE and IL-17RA on the epithelial cell surface, thereby regulating the immune function of epithelial cells in an autocrine manner. |
Immunogen | Anti- IL-17RE antibody was prepared from whole rabbit serum produced by repeated immunizations with a 16 amino acid peptide near the internal region of human IL-17RE. |
Other Names | IL-17RE Antibody, Interleukin-17 receptor E, IL-17 receptor E |
Gene, Accession # | IL17RE, Gene ID: 132014, NCBI: NP_705616, UniProt: Q8NFR9 |
Catalog # | 600-401-BV0 |
Price | $475 |
Order / More Info | IL-17RE Antibody from ROCKLAND IMMUNOCHEMICALS INC. |
Product Specific References | n/a |