Edit |   |
---|---|
Antigenic Specificity | Tyrosine Hydroxylase phospho S31 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | mouse, rat |
Isotype | n/a |
Format | immunoaffinity purified |
Size | 100 µL |
Concentration | n/a |
Applications | Immunohistochemistry, IF Microscopy, Western Blot |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Anti-Tyrosine Hydroxylase pS31 Antibody is directed against phosphorylated rat Tyrosine Hydroxylase protein. Tyrosine Hydroxylase pS31 antibodies are affinity purified from monospecific antiserum by immunoaffinity purification. Reactivity is expected from the following species based on 100% sequence homology: non-human primates. Cross reactivity from other sources has not been determined. Tyrosine Hydroxylase pS31 Antibody detects phosphorylated Tyrosine Hydroxylase protein. Tyrosine hydroxylase (TH) is the rate-limiting enzyme in the synthesis of the catecholamines dopamine and norepinephrine. TH antibodies can therefore be used as markers for dopaminergic and noradrenergic neurons in a variety of applications including depression, schizophrenia, Parkinson's disease and drug abuse. TH antibodies can also be used to explore basic mechanisms of dopamine and norepinephrine signaling. The activity of TH is also regulated by phosphorylation. Phospho-specific antibodies for the phosphorylation sites on TH can be used to great effect in studying this regulation and in identifying the cells in which TH phosphorylation occurs. |
Immunogen | Anti-Tyrosine Hydroxylase pS31 Antibody was produced repeated immunizations with a synthetic phospho-peptide corresponding to amino acid residues surrounding Ser31. |
Other Names | Tyrosine 3-monooxygenase, Tyrosine 3-hydroxylase, TH |
Gene, Accession # | Th, Gene ID: 25085, NCBI: AAA42258.1, UniProt: P04177 |
Catalog # | 600-401-E51 |
Price | $475 |
Order / More Info | Tyrosine Hydroxylase phospho S31 Antibody from ROCKLAND IMMUNOCHEMICALS INC. |
Product Specific References | n/a |