Edit |   |
Antigenic Specificity | ARTS |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | immunoaffinity purified |
Size | 100 µg |
Concentration | 1 mg/mL |
Applications | ELISA, Immunohistochemistry, IF Microscopy, Western Blot |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Anti-ARTS Antibody was affinity purified from monospecific antiserum by immunoaffinity chromatography. Cross reactivity with ARTS from other sources has not been determined. Apoptosis is related to many diseases and development. Mitochondrial proteins, such as cytochrome c, Apaf-1, and AIF play important role in apoptosis. A novel mitochondrial septin-like protein was identified recently and designated ARTS for apoptosis related protein in TGF-beta signaling pathway. ARTS that is encoded by the human septin H5/PNUTL2/CDCrel2b gene is located to mitochondria and translocates to the nucleus when apoptosis occurs. ARTS is expressed in many tissues. It enhances cell death induced by TGF-beta and, to a lesser extent, by other apoptotic agents, such as TNF-a and Fas ligand. |
Immunogen | Anti-ARTS antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic peptide corresponding to amino acids near the N-terminus of human ARTS. |
Other Names | ARTS Antibody, H5, ARTS, MART, SEP4, CE5B3, PNUTL2, hucep-7, BRADEION, hCDCREL-2, Septin-4, Apoptosis-related protein in the TGF-beta signaling pathway |
Gene, Accession # | SEPT4, Gene ID: 5414, NCBI: AAG45673, UniProt: O43236 |
Catalog # | 600-401-Y64 |
Price | $475 |
Order / More Info | ARTS Antibody from ROCKLAND IMMUNOCHEMICALS INC. |
Product Specific References | n/a |