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Antigenic Specificity | CD45RO |
Clone | UCHL1 |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG2a kappa |
Format | allophycocyanin (APC) conjugate |
Size | 500 µL |
Concentration | 0.05 mg/mL |
Applications | Flow Cytometry, Immunohistochemistry, IF Microscopy, Immunoprecipitation, Western Blot |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Allophycocyanin conjugated CD45RO Monoclonal Antibody was purified from tissue culture supernatant via affinity chromatography and is directed against human CD45RO. Reactivity is observed against human CD45RO. Cross reactivity is observed with Chimpanzee. Reactivity with CD45RO from other sources has not been tested. Anti-CD45RO is conjugated with APC under optimal conditions and the solution is free of unconjugated APC. The UCHL1 antibody reacts with the human CD45 isoform known as CD45RO, a protein tyrosine phosphatase of 220 kDa. CD45 is one of the most abundant hematopoietic markers, and is expressed on all leukocytes (the Leukocyte Common Antigen, LCA). Various isoforms are generated and expressed in cell-specific patterns. With their broad cell distribution, CD45 isoforms are critical for many leukocyte functions, regulating signal transduction and cell activation associated with the T cell receptor, B cell receptor, and IL-2 receptor. Other forms of CD45, with restricted cellular expression, include CD45R (B220), CD45RA, CD45RB, and others. The UCHL1 antibody is widely used as a marker for human CD45RO expression on thymocytes, activated memory T cells, monocytes, macrophages and granulocytes. The antibody is reported to be cross-reactive for Chimpanzee CD45RO. |
Immunogen | Anti-CD45RO Antibody (Monoclonal) was produced by repeated immunizations with CD45RO antigen. |
Other Names | Receptor-type tyrosine-protein phosphatase C, Leukocyte common antigen, PTPRC , CD45 |
Gene, Accession # | PTPRC, Gene ID: 5788, NCBI: NP_002829.3, UniProt: P08575 |
Catalog # | 200-326-N71 |
Price | $495 |
Order / More Info | CD45RO Antibody from ROCKLAND IMMUNOCHEMICALS INC. |
Product Specific References | n/a |