Edit |   |
---|---|
Antigenic Specificity | Synapsin I phospho S62 + S67 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | rat |
Isotype | n/a |
Format | immunoaffinity purified |
Size | 100 µL |
Concentration | n/a |
Applications | Western Blot |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Anti-Synapsin I pS62/67 antibody is directed against rat Synapsin I. Synapsin I pS62/67 antibody was affinity purified from monospecific antiserum by immunoaffinity purification. Immunolabeling of the synapsin I band is blocked by preadsorption with the phospho-peptide used as antigen but not be the corresponding non-phosphophorylated peptide. Reactivity is expected from the following species based on 100% sequence homology: mouse and bovine. Synapsin I pS62/67 antibody detects phosphorylated Synapsin I, which plays a key role in synaptic plasticity in brain. This effect is due in large part to the ability of the synapsins to regulate the availability of synaptic vesicles for release. The role of synapsin in synaptic plasticity and in synaptogensis is regulated by phosphorylation. Ser 549 along with Ser 62 and Ser 67 are the sites of Synapsin I that are phosphorylated by MAP kinase. Anti-Synapsin I pS62/pS67 Antibody is ideal for investigators involved in Cell Signaling, Neuroscience, Signal Transduction research. |
Immunogen | Anti-Synapsin I pS62/pS67 Antibody was produced in rabbit by repeated immunizations with synthetic phospho-peptide corresponding to amino acid residues surrounding Ser62/67 of Synapsin I protein. |
Other Names | Synapsin I, SYN1, Synapsin-1 |
Gene, Accession # | Syn1, Gene ID: 24949, NCBI: NP_001104252.1, UniProt: P09951 |
Catalog # | 612-401-E33 |
Price | $475 |
Order / More Info | Synapsin I phospho S62 + S67 Antibody from ROCKLAND IMMUNOCHEMICALS INC. |
Product Specific References | n/a |