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Antigenic Specificity | KLRA2 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | mouse, rat |
Isotype | n/a |
Format | immunoaffinity purified |
Size | 100 µg |
Concentration | 1 mg/mL |
Applications | ELISA, Immunohistochemistry, IF Microscopy, Western Blot |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Anti-KLRA2 Antibody was affinity purified from monospecific antiserum by immunoaffinity chromatography. Cross reactivity with KLRA2 from other sources has not been determined. KLRA2 (also known as Ly49B) is a member of the LY49 family of receptors in Natural Killer (NK) cells that bind to major histocompatibility complex (MHC) class 1. These proteins are classified as either activating or inhibitory receptors based on whether they possess an immunoreceptor tyrosine-based inhibitory motif (ITIM) in their cytoplasmic region (for inhibitory receptors), or an immunoreceptor tyrosine-based activation motif (ITAM) that transmits activating signals resulting in phosphorylation of several substrates. KLRA2 is thought to be an inhibitory receptor and associates with the protein tyrosine phosphatases SHP1, SHP2, and SHIP in transfected cells. This antibody is predicted to not cross-react with other LY49 receptors. |
Immunogen | Anti-KLRA2 antibody was prepared from whole rabbit serum produced by repeated immunizations with a 14 amino acid synthetic peptide near the C-terminus of mouse KLRA2. |
Other Names | KLRA2 Antibody, Ly49b, Klra30, Ly49-b, Ly49b, Killer cell lectin-like receptor 2, Lymphocyte antigen 49b, Ly-49b |
Gene, Accession # | Klra2, Gene ID: 16633, NCBI: Q60660, UniProt: Q60660 |
Catalog # | 600-401-CF7 |
Price | $475 |
Order / More Info | KLRA2 Antibody from ROCKLAND IMMUNOCHEMICALS INC. |
Product Specific References | n/a |