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Antigenic Specificity | Rabphilin 3A |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | rat |
Isotype | n/a |
Format | immunoaffinity purified |
Size | 100 µL |
Concentration | n/a |
Applications | Western Blot |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Anti-Rabphilin 3A antibody is directed against rat rabphilin 3A proteins. Anti-Rabphilin 3A antibodies are affinity purified from monospecific antiserum by immunoaffinity purification. Cross reactivity with Rab 3A from other species has not been determined, however, the sequence of the immunogen shows 100% identity to mouse, human, bovine, canine, and non-human primates, therefore, cross reactivity is expected. Rabphilin 3A antibody detects Rab 3A which is a peripheral membrane protein that binds Ca2+ and phospholipids and is attached to synaptic vesicle membranes. The expression of rabphilin 3A is reduced in an animal model of Huntington's disease. Rabphilin can be phosphorylated at Ser234 by both CAM kinase II and PKA and this phosphorylation has been suggested to regulate neuronal activity during development in a synapse-specific manner. Anti-Rabphilin 3A antibody is ideal for investigators involved in Signal Transduction, Cell Signaling, and Neuroscience research. |
Immunogen | Anti-Rabphilin 3A Antibody was produced in rabbit by repeated immunizations with synthetic peptide corresponding to amino acid residues from the C-terminal region conjugated to KLH. |
Other Names | Rabphilin 3A Homolog, Rabphilin-3A, RP3A, Rph3A, Exophilin 1, Exophilin-1 |
Gene, Accession # | Rph3a, Gene ID: 171039, UniProt: P47709 |
Catalog # | 612-401-E21 |
Price | $475 |
Order / More Info | Rabphilin 3A Antibody from ROCKLAND IMMUNOCHEMICALS INC. |
Product Specific References | n/a |