Adenovirus-9 E4 Orf1 Antibody from ROCKLAND IMMUNOCHEMICALS INC.

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Antigenic SpecificityAdenovirus-9 E4 Orf1
Clonepolyclonal
Host SpeciesRabbit
Reactive Speciesn/a
Isotypen/a
Formatimmunoaffinity purified
Size100 µg
Concentration1 mg/mL
ApplicationsELISA
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DescriptionAnti-Adenovirus-9 E4 Orf1 Antibody was affinity purified from monospecific antiserum by immunoaffinity chromatography. Cross reactivity with Adenovirus-9 E4 Orf1 from other sources has not been determined. The many different serotypes of human adenoviruses (Ad) are divided into six subgroups, of which all Ad subgroup A and B and two subgroup D Ads can elicit tumors in infected rodents. Unlike the Ads from subgroup A and B, the ones from subgroup D, Ad9 and Ad10 elicit estrogen-dependent mammary tumors as opposed to undifferentiated sarcomas. In the case of Ad9, its tumorigenicity is dependent on the product of the open reading frame (ORF) 1 of the early region 4 (E4). The tumorigenic potential of Ad9 E4 Orf1 depends on a carboxyl-terminal PDZ domain-binding motif that mediates interactions with several different membrane-associated cellular proteins such as MUPP1, PATJ, MAGI-1, ZO-2 and Dlg1. It has been suggested that Ad9 E4 Orf1 may have evolved from an ancestral cellular dUTP pyrophosphatase.
ImmunogenAnti-Ad-9 E4 Orf1 antibody was prepared from whole rabbit serum produced by repeated immunizations with a 16 amino acid synthetic peptide near the C-terminus of the Ad-9 E4 Orf1.
Other NamesAdenovirus-9 E4 Orf1 Antibody, E4-ORF1, ORF1
Gene, Accession #E4 UniProt: P89079
Catalog #600-401-X72
Price$475
Order / More InfoAdenovirus-9 E4 Orf1 Antibody from ROCKLAND IMMUNOCHEMICALS INC.
Product Specific Referencesn/a
ROCKLAND IMMUNOCHEMICALS INC.
ROCKLAND IMMUNOCHEMICALS INC.
ROCKLAND IMMUNOCHEMICALS INC.
PO Box 5199
Limerick PA 19468
P: 484-791-3823
P: 800.656.7625
F: 484.369.8654

orders@rockland.com
Technical Support: tech@rockland.com

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