SHANK1 Antibody from ROCKLAND IMMUNOCHEMICALS INC.

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Antigenic SpecificitySHANK1
CloneN22/21
Host SpeciesMouse
Reactive Specieshuman, mouse, rat
IsotypeIgG1
FormatProtein G purified
Size100 µg
Concentration1mg/mL
ApplicationsImmunohistochemistry, IF Microscopy, Western Blot
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DescriptionAnti-SHANK1 Antibody was purified by Protein G chromatography. A BLAST analysis was used to suggest cross-reactivity with SHANK1 from human, mouse, and rat based on 100% homology with the immunizing sequence. No cross-reactivity against Shank2 or Shank3. Cross-reactivity with Shank1 from other sources has not been determined. Scaffolds research. Shank proteins make up a family of scaffold proteins identified through their interaction with a variety of membrane and cytoplasmic proteins. Shank proteins at postsynaptic sites of excitatory synapses play roles in signal transmission into the postsynaptic neuron. Shank1 specifically might be relevant to human autism spectrum disorders, due to its differential role in specific cognitive processes, along with its importance for synapse structure and function in vivo.
ImmunogenSHANK1 Antibody was produced in mice by repeated immunizations raised against a fusion protein corresponding to an internal region of (SH3/PDZ domains) of rat Shank1.
Other NamesSPANK-1, SSTRIP, Shank1a, Shank1, SH3 and multiple ankyrin repeat domains protein 1, GKAP/SAPAP-interacting protein, Somatostatin receptor-interacting protein, SSTR-interacting protein, Synamon
Gene, Accession #Shank1, Gene ID: 78957, NCBI: NP_113939.2, UniProt: Q9WV48
Catalog #200-301-G43
Price$485
Order / More InfoSHANK1 Antibody from ROCKLAND IMMUNOCHEMICALS INC.
Product Specific Referencesn/a
ROCKLAND IMMUNOCHEMICALS INC.
ROCKLAND IMMUNOCHEMICALS INC.
ROCKLAND IMMUNOCHEMICALS INC.
PO Box 5199
Limerick PA 19468
P: 484-791-3823
P: 800.656.7625
F: 484.369.8654

orders@rockland.com
Technical Support: tech@rockland.com

https://www.rockland.com/

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