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Antigenic Specificity | CX3CL1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | immunoaffinity purified |
Size | 100 µg |
Concentration | 1 mg/mL |
Applications | ELISA, Immunoprecipitation, Western Blot |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Anti-CX3CL1 Antibody was affinity purified from monospecific antiserum by immunoaffinity chromatography. Cross reactivity with CX3CL1 from other sources has not been determined. Chemokines are a family of proteins associated with the trafficking of leukocytes in immune surveillance and inflammatory cell recruitment. They are classified based on the positions of key cysteine residues. CX3CL1 is a CX3C chemokine known to induce adhesion and migration of leukocytes mediated by a membrane-bound and soluble form respectively. Recent experiments have shown that CX3CL1 can suppress the production of nitrous oxide, interleukin-6, and TNF-a in activated microglia and neuronal cells, suggesting that it may act as an intrinsic inhibitor against neurotoxicity by activated microglia. Its receptor, CX3CR1, also functions as a co-receptor for HIV-1 and HIV-2 envelope fusion and virus infection, which can be inhibited by CX3CL1. |
Immunogen | Anti-CX3CL1 antibody was prepared from whole rabbit serum produced by repeated immunizations with a peptide corresponding to 18 amino acids near the N-terminus of human CX3CL1. |
Other Names | CX3CL1 Antibody, NTN, NTT, CXC3, CXC3C, SCYD1, ABCD-3, C3Xkine, fractalkine, neurotactin, FKN, A-152E5.2, Fractalkine, C-X3-C motif chemokine 1 |
Gene, Accession # | CX3CL1, Gene ID: 6376, NCBI: AAB50014, UniProt: P78423 |
Catalog # | 600-401-AR2 |
Price | $475 |
Order / More Info | CX3CL1 Antibody from ROCKLAND IMMUNOCHEMICALS INC. |
Product Specific References | n/a |