GGA2 Antibody from ROCKLAND IMMUNOCHEMICALS INC.

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Antigenic SpecificityGGA2
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman
Isotypen/a
Formatimmunoaffinity purified
Size100 µg
Concentration1.4 mg/mL
ApplicationsELISA, Immunoprecipitation, Western Blot
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DescriptionThis is an affinity purified antibody produced by immunoaffinity chromatography using the immunizing peptide after immobilization to a solid phase. GGA-2 plays a role in protein sorting and trafficking between the trans-Golgi network (TGN) and endosomes. It mediates the ARF-dependent recruitment of clathrin to the TGN and binds ubiquitinated proteins and membrane cargo molecules with a cytosolic acidic cluster-dileucine (AC-LL) motif. This gene encodes a member of the Golgi-localized, gamma adaptin ear-containing, ARF-binding (GGA) family. This family includes ubiquitous coat proteins that regulate the trafficking of proteins between the trans-Golgi network and the lysosome. These proteins share an amino-terminal VHS domain that mediates sorting of the mannose 6-phosphate receptors at the trans-Golgi network. They also contain a carboxy-terminal region with homology to the ear domain of gamma-adaptins.
ImmunogenThis affinity purified antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic peptide corresponding to an internal region near amino acids 240-270 of Human GGA2. SwissProt accession Q9UJY4. Expected to cross-react with mouse.
Other Namesrabbit anti-GGA-2 antibody, GGA2, GGA 2, Golgi associated gamma adaptin ear containing ARF binding protein 2, ADP-ribosylation factor-binding protein GGA2, Gamma-adaptin-related protein 2, VHS domain and ear domain of gamma-adaptin, Vear
Gene, Accession #GGA2, Gene ID: 23062, NCBI: NP_055859.1, UniProt: D3DWF0
Catalog #600-401-849
Price$475
Order / More InfoGGA2 Antibody from ROCKLAND IMMUNOCHEMICALS INC.
Product Specific Referencesn/a
ROCKLAND IMMUNOCHEMICALS INC.
ROCKLAND IMMUNOCHEMICALS INC.
ROCKLAND IMMUNOCHEMICALS INC.
PO Box 5199
Limerick PA 19468
P: 484-791-3823
P: 800.656.7625
F: 484.369.8654

orders@rockland.com
Technical Support: tech@rockland.com

https://www.rockland.com/

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