Tetanus Toxic Fragment C Antibody from ROCKLAND IMMUNOCHEMICALS INC.

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Antigenic SpecificityTetanus Toxic Fragment C
Clonepolyclonal
Host SpeciesRabbit
Reactive SpeciesClostridium tetani
Isotypen/a
Formatserum
Size25 µL
Concentration90 mg/mL
ApplicationsELISA, Western Blot
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DescriptionThis antibody is directed against the C fragment of Tetanus toxin derived from Clostridium tetani. The product was prepared from monospecific antiserum by delipidation and defibrination. A BLAST analysis was used to suggest cross reactivity with Clostridium tetani. Cross-reactivity with TTFC from other sources have not been determined. The illness known as Tetanus is caused by a neurotoxin produced by the anaerobic bacterium Clostridium tetani. C. tetani is commonly found in soil, feces, and on many objects lying on the ground, such as rusty metal, hence puncture wounds are a common cause of tetanus. It acts upon the presynaptic membranes of both central and peripheral nervous systems to block the release of neurotransmitters. In its toxic form tetanus neurotoxin is a 150 kDa protein, consisting of two major components: a light chain and heavy chain. The light chain contains the enzymatic portion of the toxin and is responsible for its toxic effects. The heavy chain binds to the neuron and aids delivery of the light chain to the neuron interior. A single disulfide bond links light and heavy chains.
ImmunogenThis antibody was prepared from whole rabbit serum produced by repeated immunizations with a polyhistidine-tagged TTFC fusion protein expressed in E. coli corresponding to full length TTFC.
Other Namesrabbit anti-Tetanus Toxin Fragment C Antibody , TTfC, tentoxylysin, tetX
Gene, Accession #tetX, Gene ID: 1061100, NCBI: NP_783831.1, UniProt: P04958
Catalog #100-401-894S
Price$125
Order / More InfoTetanus Toxic Fragment C Antibody from ROCKLAND IMMUNOCHEMICALS INC.
Product Specific ReferencesPubMed: 19465006
ROCKLAND IMMUNOCHEMICALS INC.
ROCKLAND IMMUNOCHEMICALS INC.
ROCKLAND IMMUNOCHEMICALS INC.
PO Box 5199
Limerick PA 19468
P: 484-791-3823
P: 800.656.7625
F: 484.369.8654

orders@rockland.com
Technical Support: tech@rockland.com

https://www.rockland.com/

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