Eaat1 Antibody from ROCKLAND IMMUNOCHEMICALS INC.
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| Antigenic Specificity | Eaat1 |
| Clone | polyclonal |
| Host Species | Chicken |
| Reactive Species | rat |
| Isotype | n/a |
| Format | IgY fraction |
| Size | 100 µg |
| Concentration | 0.99 mg/ml |
| Applications | ELISA, IF Microscopy, Western Blot |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | This affinity purified antibody is directed against rat Slc1a3. This product is an IgY fraction antibody purified from monospecific chicken egg yolks by a multi-step process which includes selective precipitation and salt fractionation followed by extensive dialysis against the buffer stated above. Blast analysis the immunogen sequence shows 100% identity with mouse and 91.7% human. Slc1a3 (or Eaat1) is widely distributed throughout the brain. It is a potassium and sodium-dependent, high-affinity amino acid transporter that mediates the uptake of L-glutamate, L-aspartate, and D-aspartate. It functions as a symporter that transports one amino acid molecule together with two or three Na+ ions and one proton, in parallel with the counter-transport of one K+ ion. It mediates Cl(-) flux that is not coupled to amino acid transport; this avoids the accumulation of negative charges due to aspartate and Na(+) symport. Slc1a3 plays a redundant role in the rapid removal of released glutamate from the synaptic cleft, which is essential for terminating the postsynaptic action of glutamate. Slc1a3 can play a role in Episodic Ataxia, Type 6 and Wernicke Encephalopathy. Anti-Slc1a3 Antibody is useful for researchers interested in SIDS, Glucose Metabolism, and Glutamate and Amino Acid Binding. |
| Immunogen | Anti-Slc1a3 antibody was prepared from eggs of chickens laid after repeated immunizations with a synthetic peptide corresponding to a N-Terminal portion of rat Slc1a3 conjugated to Keyhole Limpet Hemocyanin (KLH). |
| Other Names | Chicken Anti-Slc1a3 Antibody, Chicken Anti-Eaat1 Antibody, Excitatory amino acid transporter 1, Glial glutamate transporter, Sodium-dependent glutamate/aspartate transporter 1, GLAST, GAST-1, Slc1a3, Eaat1 |
| Gene, Accession # | Slc1a3, Gene ID: 29483, NCBI: NP_001276870.1, UniProt: P24942 |
| Catalog # | 200-901-ML1 |
| Price | $475 |
| Order / More Info | Eaat1 Antibody from ROCKLAND IMMUNOCHEMICALS INC. |
| Product Specific References | n/a |
ROCKLAND IMMUNOCHEMICALS INC.
ROCKLAND IMMUNOCHEMICALS INC.
PO Box 5199
Limerick PA 19468
P: 484-791-3823
P: 800.656.7625
F: 484.369.8654
orders@rockland.com
Technical Support: tech@rockland.com
https://www.rockland.com/
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